Chemical Space Virtual Screening against Hard-to-Drug RNA Methyltransferases DNMT2 and NSUN6.

Zimmermann, Robert A; Fischer, Tim R; Schwickert, Marvin; Nidoieva, Zarina; Schirmeister, Tanja; Kersten, Christian

Zimmermann, Robert A; Fischer, Tim R; Schwickert, Marvin; Nidoieva, Zarina; Schirmeister, Tanja; Kersten, Christian.

Afiliación

Zimmermann RA; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg-University, Staudingerweg 5, 55128 Mainz, Germany.
Fischer TR; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg-University, Staudingerweg 5, 55128 Mainz, Germany.
Schwickert M; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg-University, Staudingerweg 5, 55128 Mainz, Germany.
Nidoieva Z; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg-University, Staudingerweg 5, 55128 Mainz, Germany.
Schirmeister T; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg-University, Staudingerweg 5, 55128 Mainz, Germany.
Kersten C; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg-University, Staudingerweg 5, 55128 Mainz, Germany.

Int J Mol Sci ; 24(7)2023 Mar 24.

Article en En | MEDLINE | ID: mdl-37047081

Asunto(s)

Metiltransferasas; ARN; Simulación del Acoplamiento Molecular; ARN de Transferencia/química; ADN (Citosina-5-)-Metiltransferasas; ARNt Metiltransferasas

Palabras clave

DNMT2; NSUN6; RNA methyltransferases; chemical spaces; molecular docking; ultra-large molecular libraries; virtual screening

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: ARN / Metiltransferasas Tipo de estudio: Diagnostic_studies / Screening_studies Idioma: En Revista: Int J Mol Sci Año: 2023 Tipo del documento: Article País de afiliación: Alemania

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