Cortical maps of somatosensory perception in human.

ABSTRACT

Tactile and movement-related somatosensory perceptions are crucial for our daily lives and survival. Although the primary somatosensory cortex is thought to be the key structure of somatosensory perception, various cortical downstream areas are also involved in somatosensory perceptual processing. However, little is known about whether cortical networks of these downstream areas can be dissociated depending on each perception, especially in human. We address this issue by combining data from direct cortical stimulation (DCS) for eliciting somatosensation and data from high-gamma band (HG) elicited during tactile stimulation and movement tasks. We found that artificial somatosensory perception is elicited not only from conventional somatosensory-related areas such as the primary and secondary somatosensory cortices but also from a widespread network including superior/inferior parietal lobules and premotor cortex. Interestingly, DCS on the dorsal part of the fronto-parietal area including superior parietal lobule and dorsal premotor cortex often induces movement-related somatosensations, whereas that on the ventral one including inferior parietal lobule and ventral premotor cortex generally elicits tactile sensations. Furthermore, the HG mapping results of the movement and passive tactile stimulation tasks revealed considerable similarity in the spatial distribution between the HG and DCS functional maps. Our findings showed that macroscopic neural processing for tactile and movement-related perceptions could be segregated.