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Lack of strong innate immune reactivity renders macrophages alone unable to control productive Varicella-Zoster Virus infection in an isogenic human iPSC-derived neuronal co-culture model.
Van Breedam, Elise; Buyle-Huybrecht, Tamariche; Govaerts, Jonas; Meysman, Pieter; Bours, Andrea; Boeren, Marlies; Di Stefano, Julia; Caers, Thalissa; De Reu, Hans; Dirkx, Laura; Schippers, Jolien; Bartholomeus, Esther; Lebrun, Marielle; Sadzot-Delvaux, Catherine; Rybakowska, Paulina; Alarcón-Riquelme, Marta E; Marañón, Concepción; Laukens, Kris; Delputte, Peter; Ogunjimi, Benson; Ponsaerts, Peter.
Afiliación
  • Van Breedam E; Laboratory of Experimental Hematology (LEH), Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium.
  • Buyle-Huybrecht T; Laboratory of Experimental Hematology (LEH), Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium.
  • Govaerts J; Antwerp Center for Translational Immunology and Virology (ACTIV), Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium.
  • Meysman P; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Antwerp, Belgium.
  • Bours A; Laboratory of Experimental Hematology (LEH), Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium.
  • Boeren M; Antwerp Center for Translational Immunology and Virology (ACTIV), Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium.
  • Di Stefano J; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Antwerp, Belgium.
  • Caers T; Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing (AUDACIS), University of Antwerp, Antwerp, Belgium.
  • De Reu H; Adrem Data Lab, Department of Computer Science, University of Antwerp, Antwerp, Belgium.
  • Dirkx L; Biomedical Informatics Research Network Antwerp (Biomina), University of Antwerp, Antwerp, Belgium.
  • Schippers J; Biomedical Informatics Research Network Antwerp (Biomina), University of Antwerp, Antwerp, Belgium.
  • Bartholomeus E; Laboratory of Experimental Hematology (LEH), Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium.
  • Lebrun M; Antwerp Center for Translational Immunology and Virology (ACTIV), Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium.
  • Sadzot-Delvaux C; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Antwerp, Belgium.
  • Rybakowska P; Laboratory of Experimental Hematology (LEH), Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium.
  • Alarcón-Riquelme ME; Laboratory of Experimental Hematology (LEH), Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium.
  • Marañón C; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Antwerp, Belgium.
  • Laukens K; Laboratory of Experimental Hematology (LEH), Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium.
  • Delputte P; Flow Cytometry and Cell Sorting Core Facility (FACSUA), Laboratory of Experimental Hematology (LEH), Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium.
  • Ogunjimi B; Laboratory of Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Antwerp, Belgium.
  • Ponsaerts P; Antwerp Center for Translational Immunology and Virology (ACTIV), Vaccine and Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Antwerp, Belgium.
Front Immunol ; 14: 1177245, 2023.
Article en En | MEDLINE | ID: mdl-37287975

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Varicela / Células Madre Pluripotentes Inducidas / Infección por el Virus de la Varicela-Zóster / Herpes Zóster Límite: Humans Idioma: En Revista: Front Immunol Año: 2023 Tipo del documento: Article País de afiliación: Bélgica

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Varicela / Células Madre Pluripotentes Inducidas / Infección por el Virus de la Varicela-Zóster / Herpes Zóster Límite: Humans Idioma: En Revista: Front Immunol Año: 2023 Tipo del documento: Article País de afiliación: Bélgica