Pancreatic islet remodeling in cotadutide-treated obese mice.

Spezani, Renata; Marinho, Thatiany Souza; Macedo Cardoso, Luiz E; Aguila, Marcia Barbosa; Mandarim-de-Lacerda, Carlos Alberto

Spezani, Renata; Marinho, Thatiany Souza; Macedo Cardoso, Luiz E; Aguila, Marcia Barbosa; Mandarim-de-Lacerda, Carlos Alberto.

Afiliación

Spezani R; Laboratory of Morphometry, Metabolism, and Cardiovascular Disease, Biomedical Center, Institute of Biology, The University of the State of Rio de Janeiro, Rio de Janeiro, Brazil.
Marinho TS; Laboratory of Morphometry, Metabolism, and Cardiovascular Disease, Biomedical Center, Institute of Biology, The University of the State of Rio de Janeiro, Rio de Janeiro, Brazil.
Macedo Cardoso LE; Laboratory of Morphometry, Metabolism, and Cardiovascular Disease, Biomedical Center, Institute of Biology, The University of the State of Rio de Janeiro, Rio de Janeiro, Brazil.
Aguila MB; Laboratory of Morphometry, Metabolism, and Cardiovascular Disease, Biomedical Center, Institute of Biology, The University of the State of Rio de Janeiro, Rio de Janeiro, Brazil. Electronic address: mbaguila@uerj.br.
Mandarim-de-Lacerda CA; Laboratory of Morphometry, Metabolism, and Cardiovascular Disease, Biomedical Center, Institute of Biology, The University of the State of Rio de Janeiro, Rio de Janeiro, Brazil. Electronic address: mandarim@uerj.br.

Life Sci ; 327: 121858, 2023 Aug 15.

Article en En | MEDLINE | ID: mdl-37315839

Asunto(s)

Diabetes Mellitus Tipo 2; Resistencia a la Insulina; Células Secretoras de Insulina; Islotes Pancreáticos; Masculino; Ratones; Animales; Ratones Obesos; Diabetes Mellitus Tipo 2/metabolismo; Insulina/metabolismo; Ratones Endogámicos C57BL; Islotes Pancreáticos/metabolismo; Células Secretoras de Insulina/metabolismo; Dieta Alta en Grasa/efectos adversos; Pérdida de Peso; ADN/metabolismo

Palabras clave

Apoptosis; Beta-cell; Cell proliferation; GLP-1/glucagon; Obesity

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Resistencia a la Insulina / Islotes Pancreáticos / Diabetes Mellitus Tipo 2 / Células Secretoras de Insulina Límite: Animals Idioma: En Revista: Life Sci Año: 2023 Tipo del documento: Article País de afiliación: Brasil

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