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Discovery of Acyl-Indole Derivatives as Pan-Serotype Dengue Virus NS4B Inhibitors.
Kesteleyn, Bart; Bardiot, Dorothée; Bonfanti, Jean-François; De Boeck, Benoît; Goethals, Olivia; Kaptein, Suzanne J F; Stoops, Bart; Coesemans, Erwin; Fortin, Jérôme; Muller, Philippe; Doublet, Frédéric; Carlens, Gunter; Koukni, Mohamed; Smets, Wim; Raboisson, Pierre; Chaltin, Patrick; Simmen, Kenny; Van Loock, Marnix; Neyts, Johan; Marchand, Arnaud; Jonckers, Tim H M.
Afiliación
  • Kesteleyn B; Janssen Research and Development, Janssen Pharmaceutica NV, Turnhoutseweg 30, Beerse 2340, Belgium.
  • Bardiot D; CISTIM Leuven vzw, Bioincubator 2, Gaston Geenslaan 2, 3001 Leuven, Belgium.
  • Bonfanti JF; Janssen Infectious Diseases Discovery, Janssen-Cilag, Chaussée du Vexin, 27106 Val de Reuil, France.
  • De Boeck B; Janssen Research and Development, Janssen Pharmaceutica NV, Turnhoutseweg 30, Beerse 2340, Belgium.
  • Goethals O; Janssen Global Public Health R&D, Janssen Pharmaceutica NV, Turnhoutseweg 30, Beerse 2340, Belgium.
  • Kaptein SJF; Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, KU Leuven, Herestraat 49, 3000 Leuven, Belgium.
  • Stoops B; Janssen Research and Development, Janssen Pharmaceutica NV, Turnhoutseweg 30, Beerse 2340, Belgium.
  • Coesemans E; Janssen Research and Development, Janssen Pharmaceutica NV, Turnhoutseweg 30, Beerse 2340, Belgium.
  • Fortin J; Janssen Infectious Diseases Discovery, Janssen-Cilag, Chaussée du Vexin, 27106 Val de Reuil, France.
  • Muller P; Janssen Infectious Diseases Discovery, Janssen-Cilag, Chaussée du Vexin, 27106 Val de Reuil, France.
  • Doublet F; Janssen Infectious Diseases Discovery, Janssen-Cilag, Chaussée du Vexin, 27106 Val de Reuil, France.
  • Carlens G; CISTIM Leuven vzw, Bioincubator 2, Gaston Geenslaan 2, 3001 Leuven, Belgium.
  • Koukni M; CISTIM Leuven vzw, Bioincubator 2, Gaston Geenslaan 2, 3001 Leuven, Belgium.
  • Smets W; CISTIM Leuven vzw, Bioincubator 2, Gaston Geenslaan 2, 3001 Leuven, Belgium.
  • Raboisson P; Janssen Research and Development, Janssen Pharmaceutica NV, Turnhoutseweg 30, Beerse 2340, Belgium.
  • Chaltin P; CISTIM Leuven vzw, Bioincubator 2, Gaston Geenslaan 2, 3001 Leuven, Belgium.
  • Simmen K; Centre for Drug Design and Discovery (CD3), KU Leuven, Bioincubator 2, Gaston Geenslaan 2, Leuven 3000, Belgium.
  • Van Loock M; Janssen Research and Development, Janssen Pharmaceutica NV, Turnhoutseweg 30, Beerse 2340, Belgium.
  • Neyts J; Janssen Global Public Health R&D, Janssen Pharmaceutica NV, Turnhoutseweg 30, Beerse 2340, Belgium.
  • Marchand A; Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, KU Leuven, Herestraat 49, 3000 Leuven, Belgium.
  • Jonckers THM; Global Virus Network (GVN), Baltimore, Maryland 21201, United States.
J Med Chem ; 66(13): 8808-8821, 2023 07 13.
Article en En | MEDLINE | ID: mdl-37389813
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Dengue / Virus del Dengue Límite: Animals Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Bélgica
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Dengue / Virus del Dengue Límite: Animals Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Bélgica