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A HUWE1 defect causes PARP inhibitor resistance by modulating the BRCA1-∆11q splice variant.
Pettitt, Stephen J; Shao, Nan; Zatreanu, Diana; Frankum, Jessica; Bajrami, Ilirjana; Brough, Rachel; Krastev, Dragomir B; Roumeliotis, Theodoros I; Choudhary, Jyoti S; Lorenz, Sonja; Rust, Alistair; de Bono, Johann S; Yap, Timothy A; Tutt, Andrew N J; Lord, Christopher J.
Afiliación
  • Pettitt SJ; The CRUK Gene Function Laboratory, The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW3 6JB, UK. Stephen.Pettitt@icr.ac.uk.
  • Shao N; The CRUK Gene Function Laboratory, The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW3 6JB, UK.
  • Zatreanu D; The CRUK Gene Function Laboratory, The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW3 6JB, UK.
  • Frankum J; The CRUK Gene Function Laboratory, The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW3 6JB, UK.
  • Bajrami I; The CRUK Gene Function Laboratory, The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW3 6JB, UK.
  • Brough R; The CRUK Gene Function Laboratory, The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW3 6JB, UK.
  • Krastev DB; The CRUK Gene Function Laboratory, The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW3 6JB, UK.
  • Roumeliotis TI; The Institute of Cancer Research, London, SW3 6JB, UK.
  • Choudhary JS; The Institute of Cancer Research, London, SW3 6JB, UK.
  • Lorenz S; Max Planck Institute for Multidisciplinary Sciences, 37077, Göttingen, Germany.
  • Rust A; The Institute of Cancer Research, London, SW3 6JB, UK.
  • de Bono JS; The Institute of Cancer Research, The Royal Marsden Hospital, Downs Road, Sutton, Surrey, SM2 5PT, UK.
  • Yap TA; The Institute of Cancer Research, The Royal Marsden Hospital, Downs Road, Sutton, Surrey, SM2 5PT, UK.
  • Tutt ANJ; University of Texas MD Anderson Cancer Center, 1400 Holcombe Blvd, Houston, TX, 77030, USA.
  • Lord CJ; The CRUK Gene Function Laboratory, The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW3 6JB, UK. Andrew.Tutt@icr.ac.uk.
Oncogene ; 42(36): 2701-2709, 2023 09.
Article en En | MEDLINE | ID: mdl-37491606
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Neoplasias / Antineoplásicos Tipo de estudio: Etiology_studies Límite: Female / Humans Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2023 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Neoplasias / Antineoplásicos Tipo de estudio: Etiology_studies Límite: Female / Humans Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2023 Tipo del documento: Article