Differentially Expressed Genes Regulating Glutathione Metabolism, Protein-Folding, and Unfolded Protein Response in Pancreatic ß-Cells in Type 2 Diabetes Mellitus.

Klyosova, Elena; Azarova, Iuliia; Buikin, Stepan; Polonikov, Alexey

Klyosova, Elena; Azarova, Iuliia; Buikin, Stepan; Polonikov, Alexey.

Afiliación

Klyosova E; Laboratory of Biochemical Genetics and Metabolomics, Research Institute for Genetic and Molecular Epidemiology, Kursk State Medical University, 18 Yamskaya Street, 305041 Kursk, Russia.
Azarova I; Department of Biology, Medical Genetics and Ecology, Kursk State Medical University, 3 Karl Marx Street, 305041 Kursk, Russia.
Buikin S; Laboratory of Biochemical Genetics and Metabolomics, Research Institute for Genetic and Molecular Epidemiology, Kursk State Medical University, 18 Yamskaya Street, 305041 Kursk, Russia.
Polonikov A; Department of Biological Chemistry, Kursk State Medical University, 3 Karl Marx Street, 305041 Kursk, Russia.

Int J Mol Sci ; 24(15)2023 Jul 27.

Article en En | MEDLINE | ID: mdl-37569434

Palabras clave

apoptosis; differentially expressed genes (DEGs); gene expression; glutathione metabolism; proinsulin misfolding; protein folding; redox homeostasis; type 2 diabetes; unfolded protein response; ß-cells

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Int J Mol Sci Año: 2023 Tipo del documento: Article País de afiliación: Rusia

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