The RLR intrinsic antiviral system is expressed in neural retina and restricts lentiviral transduction of human Mueller cells.

Sauter, Monica M; Noel, Hongyu; Brandt, Curtis R

Sauter, Monica M; Noel, Hongyu; Brandt, Curtis R.

Afiliación

Sauter MM; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, 53706, USA.
Noel H; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, 53706, USA.
Brandt CR; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, 53706, USA; Department of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, WI, 53706, USA; McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, WI, 53706, USA. Electronic address: crbrandt@wisc.edu.

Exp Eye Res ; 236: 109647, 2023 11.

Article en En | MEDLINE | ID: mdl-37689341

Asunto(s)

Inmunidad Innata; Transducción de Señal; Animales; Humanos; Retina; Antivirales

Palabras clave

Gene therapy; Innate immune response; MAVS; Mueller cells; RNA sensors; Retina; Viral vectors

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Inmunidad Innata Límite: Animals / Humans Idioma: En Revista: Exp Eye Res Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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