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The USP46 complex deubiquitylates LRP6 to promote Wnt/ß-catenin signaling.
Ng, Victoria H; Spencer, Zachary; Neitzel, Leif R; Nayak, Anmada; Loberg, Matthew A; Shen, Chen; Kassel, Sara N; Kroh, Heather K; An, Zhenyi; Anthony, Christin C; Bryant, Jamal M; Lawson, Amanda; Goldsmith, Lily; Benchabane, Hassina; Hansen, Amanda G; Li, Jingjing; D'Souza, Starina; Lebensohn, Andres M; Rohatgi, Rajat; Weiss, William A; Weiss, Vivian L; Williams, Charles; Hong, Charles C; Robbins, David J; Ahmed, Yashi; Lee, Ethan.
Afiliación
  • Ng VH; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.
  • Spencer Z; Program in Cancer Biology, Vanderbilt University, Nashville, TN, 37232, USA.
  • Neitzel LR; Department of Molecular and Systems Biology and the Dartmouth Cancer Center, Geisel School of Medicine at Dartmouth College, Hanover, NH, 03755, USA.
  • Nayak A; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.
  • Loberg MA; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
  • Shen C; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20057, USA.
  • Kassel SN; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Kroh HK; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20057, USA.
  • An Z; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.
  • Anthony CC; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
  • Bryant JM; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158, USA.
  • Lawson A; Department of Pediatrics, University of California San Francisco, San Francisco, CA, 94158, USA.
  • Goldsmith L; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.
  • Benchabane H; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.
  • Hansen AG; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.
  • Li J; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.
  • D'Souza S; Department of Molecular and Systems Biology and the Dartmouth Cancer Center, Geisel School of Medicine at Dartmouth College, Hanover, NH, 03755, USA.
  • Lebensohn AM; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.
  • Rohatgi R; STEMCELL Technologies, 1618 Station Street, Vancouver, BC, V6A 1B6, Canada.
  • Weiss WA; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.
  • Weiss VL; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.
  • Williams C; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Hong CC; Departments of Biochemistry, Stanford University School of Medicine, Stanford, CA, 94305, USA.
  • Robbins DJ; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158, USA.
  • Ahmed Y; Department of Pediatrics, University of California San Francisco, San Francisco, CA, 94158, USA.
  • Lee E; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
Nat Commun ; 14(1): 6173, 2023 10 05.
Article en En | MEDLINE | ID: mdl-37798301

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Endopeptidasas / Beta Catenina / Vía de Señalización Wnt Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Endopeptidasas / Beta Catenina / Vía de Señalización Wnt Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos