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Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction.
Kefala Stavridi, Antonia; Gontier, Amandine; Morin, Vincent; Frit, Philippe; Ropars, Virginie; Barboule, Nadia; Racca, Carine; Jonchhe, Sagun; Morten, Michael J; Andreani, Jessica; Rak, Alexey; Legrand, Pierre; Bourand-Plantefol, Alexa; Hardwick, Steven W; Chirgadze, Dimitri Y; Davey, Paul; De Oliveira, Taiana Maia; Rothenberg, Eli; Britton, Sebastien; Calsou, Patrick; Blundell, Tom L; Varela, Paloma F; Chaplin, Amanda K; Charbonnier, Jean-Baptiste.
Afiliación
  • Kefala Stavridi A; Heartand Lung Research Institute, University of Cambridge, Biomedical Campus, Papworth Road, Trumpington, Cambridge CB2 0BB, UK.
  • Gontier A; Institute for Integrative Biology of the Cell (I2BC), Institute Joliot, CEA, CNRS, Univ.Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette cedex, France.
  • Morin V; Institute for Integrative Biology of the Cell (I2BC), Institute Joliot, CEA, CNRS, Univ.Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette cedex, France.
  • Frit P; Institut de Pharmacologie et Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, France.
  • Ropars V; Equipe Labellisée Ligue Contre le Cancer 2018, Toulouse, France.
  • Barboule N; Institute for Integrative Biology of the Cell (I2BC), Institute Joliot, CEA, CNRS, Univ.Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette cedex, France.
  • Racca C; Institut de Pharmacologie et Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, France.
  • Jonchhe S; Equipe Labellisée Ligue Contre le Cancer 2018, Toulouse, France.
  • Morten MJ; Institut de Pharmacologie et Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, France.
  • Andreani J; Equipe Labellisée Ligue Contre le Cancer 2018, Toulouse, France.
  • Rak A; NYU Langone Medical Center, 450 East 29th Street, NY, NY, USA York University, USA.
  • Legrand P; NYU Langone Medical Center, 450 East 29th Street, NY, NY, USA York University, USA.
  • Bourand-Plantefol A; Institute for Integrative Biology of the Cell (I2BC), Institute Joliot, CEA, CNRS, Univ.Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette cedex, France.
  • Hardwick SW; Structure-Design-Informatics, Sanofi R&D, Vitry sur Seine, France.
  • Chirgadze DY; Synchrotron SOLEIL, L'Orme des Merisiers, Saint-Aubin, Gif-sur-Yvette, France.
  • Davey P; Institute for Integrative Biology of the Cell (I2BC), Institute Joliot, CEA, CNRS, Univ.Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette cedex, France.
  • De Oliveira TM; Cryo-EM Facility, Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, UK.
  • Rothenberg E; Cryo-EM Facility, Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, UK.
  • Britton S; Oncology, R&D, AstraZeneca, Cambridge, UK.
  • Calsou P; Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge, UK.
  • Blundell TL; NYU Langone Medical Center, 450 East 29th Street, NY, NY, USA York University, USA.
  • Varela PF; Institut de Pharmacologie et Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, France.
  • Chaplin AK; Equipe Labellisée Ligue Contre le Cancer 2018, Toulouse, France.
  • Charbonnier JB; Institut de Pharmacologie et Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, France.
Nucleic Acids Res ; 51(21): 11732-11747, 2023 Nov 27.
Article en En | MEDLINE | ID: mdl-37870477
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ácido Fítico / Proteínas de Unión al ADN Límite: Animals / Humans Idioma: En Revista: Nucleic Acids Res Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ácido Fítico / Proteínas de Unión al ADN Límite: Animals / Humans Idioma: En Revista: Nucleic Acids Res Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido