Cognitive Intra-individual Variability in the Laboratory Is Associated With Greater Executive Dysfunction in the Daily Lives of Older Adults With HIV.
Cogn Behav Neurol
; 37(1): 32-39, 2024 03 01.
Article
en En
| MEDLINE
| ID: mdl-37871277
ABSTRACT
BACKGROUND:
Executive dysfunction, which is common among persons with HIV (PWH), can have an adverse impact on health behaviors and quality of life. Intra-individual variability (IIV) is a measure of within-person variability across cognitive tests that is higher in PWH and is thought to reflect cognitive dyscontrol.OBJECTIVE:
To assess whether cognitive IIV in the laboratory is associated with self-reported executive dysfunction in daily life among older PWH.METHOD:
Participants included 71 PWH aged ≥50 years who completed six subtests from the Cogstate battery and two subscales from the Frontal Systems Behavior Scale (FrSBe; self-report version). Cognitive IIV was calculated from the Cogstate as the coefficient of variation derived from age-adjusted normative T scores.RESULTS:
Cognitive IIV as measured by the Cogstate showed a significant, positive, medium-sized association with current FrSBe ratings of executive dysfunction but not disinhibition.CONCLUSION:
Higher cognitive IIV in the laboratory as measured by the Cogstate may be related to the expression of HIV-associated symptoms of executive dysfunction in daily life for older PWH.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Infecciones por VIH
/
Disfunción Cognitiva
Límite:
Aged
/
Humans
Idioma:
En
Revista:
Cogn Behav Neurol
Asunto de la revista:
NEUROLOGIA
/
PSICOLOGIA
/
PSIQUIATRIA
Año:
2024
Tipo del documento:
Article