Homer1 Protects against Retinal Ganglion Cell Pyroptosis by Inhibiting Endoplasmic Reticulum Stress-Associated TXNIP/NLRP3 Inflammasome Activation after Middle Cerebral Artery Occlusion-Induced Retinal Ischemia.

Lv, Weihao; Wu, Xiuquan; Dou, Yanan; Yan, Yiwen; Chen, Leiying; Fei, Zhou; Fei, Fei

Lv, Weihao; Wu, Xiuquan; Dou, Yanan; Yan, Yiwen; Chen, Leiying; Fei, Zhou; Fei, Fei.

Afiliación

Lv W; Department of Neurosurgery, Xijing Hospital, Air Force Medical University, No. 127, Changle West Road, Xincheng District, Xi'an 710032, China.
Wu X; Department of Neurosurgery, Xijing Hospital, Air Force Medical University, No. 127, Changle West Road, Xincheng District, Xi'an 710032, China.
Dou Y; Department of Neurosurgery, Xijing Hospital, Air Force Medical University, No. 127, Changle West Road, Xincheng District, Xi'an 710032, China.
Yan Y; Department of Neurosurgery, Xijing Hospital, Air Force Medical University, No. 127, Changle West Road, Xincheng District, Xi'an 710032, China.
Chen L; Department of Ophthalmology, Xijing Hospital, Air Force Medical University, No. 127, Changle West Road, Xincheng District, Xi'an 710032, China.
Fei Z; Department of Neurosurgery, Xijing Hospital, Air Force Medical University, No. 127, Changle West Road, Xincheng District, Xi'an 710032, China.
Fei F; Department of Ophthalmology, Xijing Hospital, Air Force Medical University, No. 127, Changle West Road, Xincheng District, Xi'an 710032, China.

Int J Mol Sci ; 24(23)2023 Nov 27.

Article en En | MEDLINE | ID: mdl-38069134

Asunto(s)

Isquemia Encefálica; Daño por Reperfusión; Enfermedades de la Retina; Animales; Ratones; Isquemia Encefálica/metabolismo; Estrés del Retículo Endoplásmico; Proteínas de Andamiaje Homer/metabolismo; Infarto de la Arteria Cerebral Media/complicaciones; Infarto de la Arteria Cerebral Media/metabolismo; Inflamasomas/metabolismo; Inflamación/metabolismo; Isquemia/metabolismo; Proteína con Dominio Pirina 3 de la Familia NLR/metabolismo; Piroptosis; Daño por Reperfusión/metabolismo; Enfermedades de la Retina/etiología; Enfermedades de la Retina/metabolismo; Células Ganglionares de la Retina/metabolismo

Palabras clave

AMPK; ER stress; Homer1; MCAO-induced retinal ischemia; RGCs; pyroptosis

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedades de la Retina / Daño por Reperfusión / Isquemia Encefálica Límite: Animals Idioma: En Revista: Int J Mol Sci Año: 2023 Tipo del documento: Article País de afiliación: China

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