Reactivation of Epstein-Barr virus in SFTSV infected patients.
Infect Med (Beijing)
; 2(3): 195-201, 2023 Sep.
Article
en En
| MEDLINE
| ID: mdl-38073887
ABSTRACT
Background:
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging hemorrhagic fever caused by a tick-borne bunyavirus SFTSV with case fatality up to 30%. The reactivation of Epstein-Barr virus (EBV) has been proven to occur in individuals with various immune suppression conditions.Methods:
Here, we diagnosed 22 SFTSV infected patients with PCR in a hospital in Shandong Province, China in 2020. To understand the consequences of SFTSV infection leading to EBV reactivation, we examined EBV reactivation in SFTSV-infected patients with PCR and RT-PCR.Results:
We found that EBV was reactivated in 18.2% (4/22) of SFTS patients, suggesting that EBV reactivation is common in SFTS patients. Compared with SFTS patients without EBV reactivation, SFTS patients with EBV-reactivation had a significantly lower median level of serum albumin (32.45 g/L vs. 26.95 g/L, p = 0.03) and a significantly higher median number of urine red blood cells (0 cells/µL vs. 9 cells/µL, p = 0.04).Conclusion:
SFTS infection can reactivate EBV in patients, which may make the clinical condition of patients worsen.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
Infect Med (Beijing)
Año:
2023
Tipo del documento:
Article
País de afiliación:
China