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The Next Chapter in Immunotherapy and Radiation Combination Therapy: Cancer-Specific Perspectives.
Wisdom, Amy J; Barker, Christopher A; Chang, Joe Y; Demaria, Sandra; Formenti, Silvia; Grassberger, Clemens; Gregucci, Fabiana; Hoppe, Bradford S; Kirsch, David G; Marciscano, Ariel E; Mayadev, Jyoti; Mouw, Kent W; Palta, Manisha; Wu, Cheng-Chia; Jabbour, Salma K; Schoenfeld, Jonathan D.
Afiliación
  • Wisdom AJ; Harvard Radiation Oncology Program, Boston, Massachusetts.
  • Barker CA; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Chang JY; Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Demaria S; Department of Radiation Oncology, Weill Cornell Medicine, New York, New York.
  • Formenti S; Department of Radiation Oncology, Weill Cornell Medicine, New York, New York.
  • Grassberger C; Department of Radiation Oncology, University of Washington, Fred Hutch Cancer Center, Seattle, Washington.
  • Gregucci F; Department of Radiation Oncology, Weill Cornell Medicine, New York, New York.
  • Hoppe BS; Department of Radiation Oncology, Mayo Clinic, Jacksonville, Florida.
  • Kirsch DG; Department of Radiation Oncology, University of Toronto, Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
  • Marciscano AE; Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts.
  • Mayadev J; Department of Radiation Oncology, UC San Diego School of Medicine, San Diego, California.
  • Mouw KW; Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Palta M; Department of Radiation Oncology, Duke Cancer Center, Durham, North Carolina.
  • Wu CC; Department of Radiation Oncology, Columbia University Irving Medical Center, New York, New York.
  • Jabbour SK; Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey. Electronic address: jabbousk@cinj.rutgers.edu.
  • Schoenfeld JD; Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, Massachusetts. Electronic address: Jonathan_Schoenfeld@dfci.harvard.edu.
Int J Radiat Oncol Biol Phys ; 118(5): 1404-1421, 2024 Apr 01.
Article en En | MEDLINE | ID: mdl-38184173
ABSTRACT
Immunotherapeutic agents have revolutionized cancer treatment over the past decade. However, most patients fail to respond to immunotherapy alone. A growing body of preclinical studies highlights the potential for synergy between radiation therapy and immunotherapy, but the outcomes of clinical studies have been mixed. This review summarizes the current state of immunotherapy and radiation combination therapy across cancers, highlighting existing challenges and promising areas for future investigation.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Límite: Humans Idioma: En Revista: Int J Radiat Oncol Biol Phys Año: 2024 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Límite: Humans Idioma: En Revista: Int J Radiat Oncol Biol Phys Año: 2024 Tipo del documento: Article