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Beam monitor chamber calibration of a synchro-cyclotron high dose rate per pulse pulsed scanned proton beam.
Vidal, Marie; Gérard, Anaïs; Floquet, Vincent; Forthomme, Julien; Christensen, Jeppe Brage; Almhagen, Erik; Grusell, Erik; Heymans, Vincent; Rossomme, Séverine; Dumas, Serge; Trimaud, Richard; Hérault, Joël.
Afiliación
  • Vidal M; Institut Méditerranéen de Protonthérapie-Centre Antoine Lacassagne, Fédération Claude Lalanne, Nice, France.
  • Gérard A; Institut Méditerranéen de Protonthérapie-Centre Antoine Lacassagne, Fédération Claude Lalanne, Nice, France.
  • Floquet V; Institut Méditerranéen de Protonthérapie-Centre Antoine Lacassagne, Fédération Claude Lalanne, Nice, France.
  • Forthomme J; IBA Proton Therapy, Louvain-la-Neuve, Belgium.
  • Christensen JB; DTU Health Tech, Technical University of Denmark, Roskilde, Denmark.
  • Almhagen E; Department of Radiation Safety and Security, Paul Scherrer Institute, PSI Villigen, Switzerland.
  • Grusell E; Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Immunology, Genetics and Pathology, Medical Radiation Science-Skandion Clinics Uppsala, Sweden.
  • Heymans V; Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Immunology, Genetics and Pathology, Medical Radiation Science-Skandion Clinics Uppsala, Sweden.
  • Rossomme S; IBA Proton Therapy, Louvain-la-Neuve, Belgium.
  • Dumas S; IBA Dosimetry Schwarzenbrück, Germany.
  • Trimaud R; Institut Méditerranéen de Protonthérapie-Centre Antoine Lacassagne, Fédération Claude Lalanne, Nice, France.
  • Hérault J; Institut Méditerranéen de Protonthérapie-Centre Antoine Lacassagne, Fédération Claude Lalanne, Nice, France.
Phys Med Biol ; 69(8)2024 Apr 03.
Article en En | MEDLINE | ID: mdl-38252970
ABSTRACT
Objective. Ionization chambers, mostly used for beam calibration and for reference dosimetry, can show high recombination effects in pulsed high dose rate proton beams. The aims of this paper are first, to characterize the linearity response of newly designed asymmetrical beam monitor chambers (ABMC) in a 100-226 MeV pulsed high dose rate per pulse scanned proton beam; and secondly, to calibrate the ABMC with a PPC05 (IBA Dosimetry) plane parallel ionization chamber and compare to calibration with a home-made Faraday cup (FC).Approach. The ABMC response linearity was evaluated with both the FC and a PTW 60019 microDiamond detector. Regarding ionometry-based ABMC calibration, recombination factors were evaluated theoretically, then numerically, and finally experimentally measured in water for a plane parallel ionization chamber PPC05 (IBA Dosimetry) throughkssaturation curves. Finally, ABMC calibration was also achieved with FC and compared to the ionometry method for 7 energies.Main results. Linearity measurements showed that recombination losses in the new ABMC design were well taken into account for the whole range of the machine dose rates. The two-voltage-method was not suitable for recombination correction, but Jaffé's plots analysis was needed, emphasizing the current IAEA TRS-398 reference protocol limitations. Concerning ABMC calibration, FC based absorbed dose estimation and PPC05-based absorbed dose estimation differ by less than 6.3% for the investigated energies.Significance.So far, no update on reference dosimetry protocols is available to estimate the absorbed dose in ionization chambers for clinical high dose rate per pulse pulsed scanned proton beams. This work proposes a validation of the new ABMC design, a method to take into account the recombination effect for ionometry-based ABMC calibration and a comparison with FC dose estimation in this type of proton beams.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Protones / Radiactividad Tipo de estudio: Guideline / Prognostic_studies Idioma: En Revista: Phys Med Biol Año: 2024 Tipo del documento: Article País de afiliación: Francia

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Protones / Radiactividad Tipo de estudio: Guideline / Prognostic_studies Idioma: En Revista: Phys Med Biol Año: 2024 Tipo del documento: Article País de afiliación: Francia