Macrophage niche imprinting as a determinant of macrophage identity and function.
Cell Immunol
; 399-400: 104825, 2024.
Article
en En
| MEDLINE
| ID: mdl-38648700
ABSTRACT
Macrophage niches are the anatomical locations within organs or tissues consisting of various cells, intercellular and extracellular matrix, transcription factors, and signaling molecules that interact to influence macrophage self-maintenance, phenotype, and behavior. The niche, besides physically supporting macrophages, imposes a tissue- and organ-specific identity on the residing and infiltrating monocytes and macrophages. In this review, we give examples of macrophage niches and the modes of communication between macrophages and surrounding cells. We also describe how macrophages, acting against their immune defensive nature, can create a hospitable niche for pathogens and cancer cells.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Macrófagos
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Cell Immunol
Año:
2024
Tipo del documento:
Article