The control of transitions along the main body axis.
Curr Top Dev Biol
; 159: 272-308, 2024.
Article
en En
| MEDLINE
| ID: mdl-38729678
ABSTRACT
Although vertebrates display a large variety of forms and sizes, the mechanisms controlling the layout of the basic body plan are substantially conserved throughout the clade. Following gastrulation, head, trunk, and tail are sequentially generated through the continuous addition of tissue at the caudal embryonic end. Development of each of these major embryonic regions is regulated by a distinct genetic network. The transitions from head-to-trunk and from trunk-to-tail development thus involve major changes in regulatory mechanisms, requiring proper coordination to guarantee smooth progression of embryonic development. In this review, we will discuss the key cellular and embryological events associated with those transitions giving particular attention to their regulation, aiming to provide a cohesive outlook of this important component of vertebrate development.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Regulación del Desarrollo de la Expresión Génica
/
Tipificación del Cuerpo
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Curr Top Dev Biol
Año:
2024
Tipo del documento:
Article
País de afiliación:
Portugal