Isotype of antibodies responsible for immune lysis in Trypanosoma cruzi infected mice.
Immunol Lett
; 7(2): 91-7, 1983.
Article
en En
| MEDLINE
| ID: mdl-6418640
ABSTRACT
Serum obtained from mice infected with Trypanosoma cruzi have antibodies able to induce immune lysis in presence of complement. Gel filtration in Sephadex G-200 and affinity chromatography with rabbit anti-mouse IgG and protein A-Sepharose showed that the antibodies responsible for the immune serum lytic activity are exclusively located in Ig of IgG isotype, including IgG1, IgG2a, IgG2b and probably IgG3. It is suggested that antibodies responsible for protection against T. cruzi infection and antibodies responsible for immune lysis are the same.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Trypanosoma cruzi
/
Inmunoglobulina G
/
Enfermedad de Chagas
Límite:
Animals
Idioma:
En
Revista:
Immunol Lett
Año:
1983
Tipo del documento:
Article