A conformationally constrained vasopressin analog with antidiuretic antagonistic activity.
Science
; 226(4673): 443-5, 1984 Oct 26.
Article
en En
| MEDLINE
| ID: mdl-6541806
ABSTRACT
Application of information derived from a three-dimensional model of vasopressin bound to its antidiuretic receptor resulted in the design and synthesis of a bicyclic vasopressin analog, [5,8-cyclo(1-beta-mercaptopropionic acid,2-phenylalanine,5-aspartic acid,8-lysine)]vasopressin. The analog acts as an antagonist of the antidiuretic activity of vasopressin.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Arginina Vasopresina
/
Lipresina
Límite:
Animals
Idioma:
En
Revista:
Science
Año:
1984
Tipo del documento:
Article