Biosynthesis of polymyxin E by a cell-free enzyme system. II. Synthesis of enzyme-bound octanoyldiaminobutyric acid.
J Biochem
; 88(1): 285-8, 1980 Jul.
Article
en En
| MEDLINE
| ID: mdl-6773931
ABSTRACT
A partially purified enzyme of Aerobacillus polyaerogenes, which produces polymyxin E, activates L-2,4-diaminobutyric acid and binds it as a thioester. The incubation of the enzyme preparation with octanoyl coenzyme A and L-2,4-diaminobutyric acid in the presence of ATP and an ammonium sulfate fraction yields octanoyldiaminobutyric acid thioesterified to the enzyme.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Bacillus
/
Colistina
Idioma:
En
Revista:
J Biochem
Año:
1980
Tipo del documento:
Article