Chromosome condensation in Xenopus mitotic extracts without histone H1.
Science
; 262(5142): 2033-5, 1993 Dec 24.
Article
en En
| MEDLINE
| ID: mdl-8266099
ABSTRACT
The contribution of histone H1 to mitotic chromosome condensation was examined with the use of a cell-free extract from Xenopus eggs, which transforms condensed sperm nuclei into metaphase chromosomes. When H1 was removed from the extract, the resultant metaphase chromosomes were indistinguishable from those formed in complete extract. Nucleosomal spacing was the same for both. Thus, H1 is not required for the structural reorganization that leads to condensed metaphase chromosomes in this egg extract.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Histonas
/
Cromosomas
/
Mitosis
Límite:
Animals
Idioma:
En
Revista:
Science
Año:
1993
Tipo del documento:
Article
País de afiliación:
Japón