Plasma cell leukaemia mimicking acute monocytic leukaemia in the course of multiple myeloma.
Nouv Rev Fr Hematol (1978)
; 35(4): 419-22, 1993 Aug.
Article
en En
| MEDLINE
| ID: mdl-8414961
ABSTRACT
We report a case of acute leukaemia occurring early in the course of IgA multiple myeloma. Ultrastructural studies, immunophenotyping and karyotyping were required to identify the origin and clonality of the leukaemic cells. Although ultrastructural examination of the blast cells revealed both monocytoid and plasma cell features, all cells expressed the CD 38 antigen and intracytoplasmic kappa light chains, while karyotyping revealed a clone with numerous abnormalities, leading to the diagnosis of clonal plasma cell disease. The occurrence of leukaemia in multiple myeloma is discussed.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Leucemia de Células Plasmáticas
/
Leucemia Monocítica Aguda
/
Neoplasias Primarias Secundarias
/
Mieloma Múltiple
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
Nouv Rev Fr Hematol (1978)
Año:
1993
Tipo del documento:
Article
País de afiliación:
Francia