A Case of Cytomegalovirus-associated Giant Gastric Ulcer in a Patient Who Healed by Discontinuing Immunosuppressive Therapy
Article
en Ko
| WPRIM
| ID: wpr-112437
Biblioteca responsable:
WPRO
ABSTRACT
Cytomegalovirus (CMV) is not a rare infection and is frequently observed in immuoncompromised patients. CMV infection is usually asymptomatic in immunocompetent patients however it can be a major cause of morbidity and mortality in immunocompromised patients. The diagnosis of CMV gastric ulcer is not easy because of the absence of characteristic endoscopic features and the difficulty in the identification of infection by routine histologic examinations. We experienced a case of CMV-associated giant gastric ulcer in a patient receiving immunosuppressive therapy. She was a 45-year-old woman with dermatomyositis and had received steroid therapy to control her disease. Epigastric pain developed during therapy and upper endoscopy revealed a gastric ulcer. Despite proton pump inhibitor therapy, her epigastric pain aggravated and follow-up endoscopy revealed a huge gastric ulcer approximately 10 cm in diameter. Histologic findings showed intracellular inclusion bodies after immunostaining which confirmed CMV-associated gastric ulcer. Steroid therapy was discontinued and she received proton pump inhibitors without antiviral agents. Her symptoms improved and follow-up endoscopy revealed successful healing of the CMV-associated gastric ulcer. If an unusual gastric ulcer develops in the immunocompromised patients, CMV gastric ulcer should be suspected and examination for inclusion bodies using CMV immunostaining should be considered.
Palabras clave
Texto completo:
1
Banco de datos:
WPRIM
Asunto principal:
Antivirales
/
Esteroides
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Úlcera Gástrica
/
Enfermedad del Almacenamiento de Glucógeno Tipo VI
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Cuerpos de Inclusión
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Estudios de Seguimiento
/
Mortalidad
/
Huésped Inmunocomprometido
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Bombas de Protones
/
Citomegalovirus
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
Idioma:
Ko
Revista:
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Año:
2015
Tipo del documento:
Article