Positive seroconversion rate of hepatitis B antibody after hepatitis B vaccination by birth weight and gestational age / 대한주산의학회잡지
Korean Journal of Perinatology
; : 37-41, 2008.
Article
en Ko
| WPRIM
| ID: wpr-117729
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVE:
Previous studies have reported that the immune response of hepatitis B vaccine is decreased in preterm or low birth weight babies compared to healthy term babies. To evaluate this notion, we investigated the positive seroconversion rate of hepatitis B antibody after hepatitis B vaccination according to gestational age and birth weight.METHODS:
We retrospectively studied medical records about the positive seroconversion rate of a total of 968 infants who were given DNA recombinant hepatitis B vaccine as scheduled at Il Sin Christian Hospital, Busan from January 2002 to Mar 2007.RESULTS:
The postive seroconversion failure rate (non-responder or poor-responder) of hepatitis B antibody by gestational age was 15.6% (28 weeks, 32 weeks, 1,000 g, 1,500 g, 2,000 g).CONCLUSION:
The seropositive rate of hepatitis B antibody after hepatitis B vaccination decreased as the gestational age and the birth weight decreased. And gestational age more than 37 weeks and birth weight above 2,000 g were independently associated with a higher seropositive rate of hepatitis B antibody after hepatitis B vaccination.Palabras clave
Texto completo:
1
Banco de datos:
WPRIM
Asunto principal:
Peso al Nacer
/
ADN
/
Recién Nacido de Bajo Peso
/
Registros Médicos
/
Estudios Retrospectivos
/
Edad Gestacional
/
Vacunación
/
Vacunas contra Hepatitis B
/
Parto
/
Hepatitis
Tipo de estudio:
Observational_studies
Límite:
Humans
/
Infant
/
Newborn
Idioma:
Ko
Revista:
Korean Journal of Perinatology
Año:
2008
Tipo del documento:
Article