Development of second primary cancer in Korean breast cancer survivors
Annals of Surgical Treatment and Research
; : 287-292, 2017.
Article
en En
| WPRIM
| ID: wpr-134102
Biblioteca responsable:
WPRO
ABSTRACT
PURPOSE:
Breast cancer survivors have slightly increased the risk of second primary cancers. Breast, colon, uterine, and ovarian cancers are common secondary cancers in breast cancer survivors. In this study, we assessed the development of second primary cancers of breast cancer survivors in Korea.METHODS:
Medical records of patients with breast cancer in 3 tertiary medical institutions were reviewed retrospectively. We evaluated secondary malignancy diagnosed at least 2 months after the breast cancer diagnosis. Based on the International Classification of Disease-9 codes of malignancies, secondary primary breast cancer records were evaluated with person-year adjustment. The standardized incidence ratio (SIR) was assessed using national cancer incidence.RESULTS:
A total of 3,444 treatment records were included from 3 medical centers. The cumulative incidence of overall second primary cancers was 2.8% (n = 93). The SIR was significantly higher in all sites (1.56; 95% confidence interval [CI], 1.26–1.91), endometrial cancer (5.65; 95% CI, 2.06–12.31), biliary tract cancer (3.96; 95% CI, 1.19–8.60), and thyroid cancer (2.29; 95% CI, 1.67–3.08).CONCLUSION:
The incidence of cancer was higher in breast cancer survivors compared to general population. Surveillance of secondary cancer in this group should be recommended individually considering the benefit related to the prognosis of primary breast cancer.Palabras clave
Texto completo:
1
Banco de datos:
WPRIM
Asunto principal:
Neoplasias Ováricas
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Pronóstico
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Neoplasias del Sistema Biliar
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Mama
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Neoplasias de la Mama
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Neoplasias de la Tiroides
/
Registros Médicos
/
Incidencia
/
Estudios Retrospectivos
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Clasificación
Tipo de estudio:
Diagnostic_studies
/
Incidence_studies
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Observational_studies
/
Prognostic_studies
/
Screening_studies
Límite:
Female
/
Humans
País/Región como asunto:
Asia
Idioma:
En
Revista:
Annals of Surgical Treatment and Research
Año:
2017
Tipo del documento:
Article