Interstitial Pneumonitis in a Patient with Chronic Hepatitis C and Chronic Renal Failure on Interferon Therapy / 대한소화기학회지
The Korean Journal of Gastroenterology
; : 47-52, 2011.
Article
en En
| WPRIM
| ID: wpr-153658
Biblioteca responsable:
WPRO
ABSTRACT
After 4-months of alpha interferon (IFN-alpha), a 64-year old woman with chronic hepatitis C developed a cough and dyspnea and showed diffuse infiltrative opacities on her chest X-ray. Her symptoms persisted after stopping the IFN-alpha therapy. Pulmonary function testing revealed a reduced forced vital capacity. High-resolution computed tomography of the lung showed peripheral and peribronchovascular ground glass attenuation and consolidation associated with reticulation. Bronchoalveolar lavage was performed for further evaluation and showed a lymphocyte level of 8.2%, an uncommon finding in IFN-alpha-induced interstitial pneumonitis. We performed a lung biopsy to diagnose her disease and it suggested interstitial pneumonitis. This was considered to be due to the immunomodulatory effects of INF-alpha. Although rare, any sign of significant pulmonary involvement should be evaluated.
Palabras clave
Texto completo:
1
Banco de datos:
WPRIM
Asunto principal:
Antivirales
/
Pruebas de Función Respiratoria
/
Tomografía Computarizada por Rayos X
/
Interferón-alfa
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Enfermedades Pulmonares Intersticiales
/
Lavado Broncoalveolar
/
Hepatitis C Crónica
/
Fallo Renal Crónico
Límite:
Female
/
Humans
Idioma:
En
Revista:
The Korean Journal of Gastroenterology
Año:
2011
Tipo del documento:
Article