Two Cases of Metronidazole-induced Encephalopathy / 대한소화기학회지
The Korean Journal of Gastroenterology
; : 195-200, 2005.
Article
en Ko
| WPRIM
| ID: wpr-17264
Biblioteca responsable:
WPRO
ABSTRACT
Metronidazole is a 5-nitroimidazole compound known as an antimicrobial agent widely used for the treatment of protozoal infection, anaerobic infection, Helicobacter pylori infection and hepatic encephalopathy. It may produce a number of neurologic side effects including peripheral neuropathy, seizure, encephalopathy, ataxic gait and dysarthritic speech. There have been ten or more reports of metronidazole-induced encephalopathy in the literatures including a few reports of brain imaging changes by magnetic resonance images (MRI). However, none of the case of metronidazole-induced encephalopathy in patients with hepatic encephalopathy has been reported yet. Recently, we experienced two cases of metronidazole-induced encephalopathy in patients with liver cirrhosis caused by chronic hepatitis B, which were diagnosed by brain MRI and MR spectroscopy. In this report, we present 2 cases of metronidazole-induced encephalopathy with MR imaging and MR spectroscopic changes including follow- up imaging performed after the discontinuation of the metronidazole with a review of the literatures.
Palabras clave
Texto completo:
1
Banco de datos:
WPRIM
Asunto principal:
Encefalopatías
/
Resumen en Inglés
/
Imagen por Resonancia Magnética
/
Espectroscopía de Resonancia Magnética
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Metronidazol
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Antiinfecciosos
Límite:
Female
/
Humans
/
Male
Idioma:
Ko
Revista:
The Korean Journal of Gastroenterology
Año:
2005
Tipo del documento:
Article