Fine Needle Aspiration Cytology of Parathyroid Lesions
Korean Journal of Pathology
; : 466-471, 2013.
Article
en En
| WPRIM
| ID: wpr-189503
Biblioteca responsable:
WPRO
ABSTRACT
BACKGROUND:
There has been an increase in the use of fine needle aspiration cytology (FNAC) for the diagnosis of parathyroid lesions (PLs). Differentiation between a thyroid lesion and a PL is not easy because of their similar features. We reviewed parathyroid aspirates in our institution and aimed to uncover trends in diagnostic criteria.METHODS:
We selected 25 parathyroid aspirates (from 6 men and 19 women) confirmed surgically or immunohistochemically from 2006 to 2011.RESULTS:
Major architectural findings of PLs include scattered naked nuclei, loose clusters, a papillary pattern with a fibrovascular core, tight clusters, and a follicular pattern. These architectures were commonly admixed with one another. Cytological features included anisokaryosis, stippled chromatin, a well-defined cell border, and oxyphilic cytoplasm. Eighteen of the 25 patients were diagnosed with PL using FNAC. Seven patients had been misdiagnosed with atypical cells (n=2), benign follicular cells (n=2), adenomatous goiter (n=2) and metastatic carcinoma (n=1) in FNAC. Using clinicoradiologic data, the sensitivity of the cytological diagnosis was 86.7%. The cytological sensitivity decreased to 50% without this information.CONCLUSIONS:
FNAC of PL is easily confused with thyroid lesions. A combination of cytological parameters and clinical data will be required to improve the diagnostic sensitivity of PLs.Palabras clave
Texto completo:
1
Banco de datos:
WPRIM
Asunto principal:
Glándula Tiroides
/
Cromatina
/
Citoplasma
/
Biopsia con Aguja Fina
/
Bocio
Límite:
Humans
/
Male
Idioma:
En
Revista:
Korean Journal of Pathology
Año:
2013
Tipo del documento:
Article