The Role of Bile Carcinoembryonic Antigen in Diagnosing Bile Duct Cancer
Journal of Korean Medical Science
; : 855-858, 2003.
Article
en En
| WPRIM
| ID: wpr-28623
Biblioteca responsable:
WPRO
ABSTRACT
It is known that the fluids bathing tumors might contain a higher level of the carcinoembryonic antigen (CEA) than those found in the blood. Therefore, we evaluated the role of bile CEA in diagnosing bile duct cancer. One hundred and thirty two patients were prospectively studied. The patients were divided into 3 groups the bile duct cancer (n=32), pancreatic cancer (n=16), and benign biliary diseases (n=84) groups. Bile samples were obtained on the next day of the biliary drainage procedures. The mean bile CEA level in those with bile duct cancer (120.6+/-156.9 ng/mL) was significantly higher than those with pancreatic cancer and benign biliary diseases (32.0+/-28.5 ng/mL, 29.3+/-56.3 ng/mL). Using the level of 20 ng/mL, the sensitivity and specificity of bile CEA in the diagnosis of bile duct cancer from benign biliary diseases were 65.6% and 66.7%, respectively. Both the bile CEA and total bilirubin level were found to be an independent factor linked to bile duct cancer. This study result suggests that bile CEA level is a useful supplementary test for diagnosing bile duct cancer.
Palabras clave
Texto completo:
1
Banco de datos:
WPRIM
Asunto principal:
Bilis
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Neoplasias de los Conductos Biliares
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Antígeno Carcinoembrionario
/
Valor Predictivo de las Pruebas
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Estudios Retrospectivos
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Sensibilidad y Especificidad
/
Estadística
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
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Prognostic_studies
Límite:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
Idioma:
En
Revista:
Journal of Korean Medical Science
Año:
2003
Tipo del documento:
Article