Building the Reference Range of Low Hemoglobin Density(LHD%) of Healthy Population in Humen District of Guangdong and Discuss Its Clinical Application Value / 现代检验医学杂志
Journal of Modern Laboratory Medicine
; (4): 86-88,91, 2017.
Article
en Zh
| WPRIM
| ID: wpr-606633
Biblioteca responsable:
WPRO
ABSTRACT
Objective To establishe the reference range of low hemoglobin density (LHD %) of health population in Humen District of Guangdong,and discuss the clinical application value.Methods Randomly selected from January 2015 to September 2016 in Humen Hospital of Dongguan City physical examination of 1 650 cases of healthy people as control group,and selected the same period by the clinical diagnosis of iron deficiency anemia (iron-deficiency anemia,IDA) group,67 cases of patients with IDA Sysmex XT-1800i fully automatic blood analyzer were used respectively to detect blood routine,and then based on the average haemoglobin concentration (mean corpuscular hemoglobin concentration,MCHC),calculate the LHD%,and the calculation results were analyzed.Results The control healthy crowd LHD% value was 2.41% ± 0.85 %,95% reference range was 0.74 % ~4.08%,male was higher than the female,the difference was statistically significant (t =3.209,P<0.05).IDA patients before treatment LHD% was 30.97% ± 18.65%,significantly higher than the control group,the difference was statistically significant (t=19.536,P< 0.01),and with the level of hemoglobin (Hb) showed a negative correlation (r=-0.4313).LHD% values after treatment in patients with IDA group were significantly lower,but the recovery speed was slower than the Hb and MCHC.By ROC curve analysis,when the cut-off of LHD% value was 4.10%,the LHD% for IDA early diagnostic sensitivity of 96.78%,specificity of 100%.Conclusion Established the reference range of low hemoglobin density (LHD %) of healthy population in Humen district of Guangdong,and LHD% is IDA good indicator of early diagnosis and curative effect of dynamic monitoring.
Texto completo:
1
Banco de datos:
WPRIM
Tipo de estudio:
Prognostic_studies
/
Screening_studies
Idioma:
Zh
Revista:
Journal of Modern Laboratory Medicine
Año:
2017
Tipo del documento:
Article