Outcome of surgical intervention for non-small-cell lung cancer patients with pleural carcinomatosis first detected at thoracotomy / 中华胸心血管外科杂志
Chinese Journal of Thoracic and Cardiovascular Surgery
; (12): 522-526, 2017.
Article
en Zh
| WPRIM
| ID: wpr-662834
Biblioteca responsable:
WPRO
ABSTRACT
Objective To describe the effects of surgical intervention on the prognosis in non-small-cell lung cancer patients with pleural carcinomatosis detected at thoracotomy.Methods Retrospectively analyzed clinical data from 54 patients who have unexpected malignant pleural nodules and/or malignant pleural effusions first detected at thoracotomy from January 2009 and December 2013.The effects of surgical intervention on the prognosis were also discussed.Results Sixteen cases had only biopsy,whereas 38 (70.4%) cases had primary tumor resection.The median survival time of 54 patients with pleural carcinomatosis were 23 months.The overall 1 and 5-year survival rates were 64% and 18%,respectively.Primary tumor resection had significantly better outcome compared with biopsy(MSTrespectively,24 vs 15 months,5-year survival rate 39% vs 6%,P <0.05).Univariate analysis showed that primary tumor resection,no smoking history,lower T and N stage has favorable survival(P < 0.05).Multivariate analysis showed that the best N stage(P =0.002) and adenocarcinoma(P =0.035) were favorable prognostic factors in these patients.Conclusion For patients with pleural careinomatosis first detected at thoracotomy,limited primary tumor resection may have survival benefits,lower T and N stage for them was associated with better survival.
Texto completo:
1
Banco de datos:
WPRIM
Tipo de estudio:
Prognostic_studies
Idioma:
Zh
Revista:
Chinese Journal of Thoracic and Cardiovascular Surgery
Año:
2017
Tipo del documento:
Article