The Response of the Injured Articular Cartilage of Rabbit Knee after Injection of Autologous Blood
Journal of the Korean Academy of Rehabilitation Medicine
; : 406-412, 2005.
Article
en Ko
| WPRIM
| ID: wpr-722437
Biblioteca responsable:
WPRO
ABSTRACT
OBJECTIVE: To evaluate the effects of proliferant by injecting blood into the articular cartilage defect. METHOD: The patella of rabbits were dislocated laterally and 2 mm circular and 2 mm depth full-thickness defect was made in the articular cartilage. We injected 0.2 cc autologous blood to the right defect and normal saline to the left one at 1 week after operation for six times with a 1 week interval. After injection for six weeks, the articular cartilage defect were obtained and stained with H-E and S-100. RESULTS: The surface of the saline-injected group was easily distinguishable from the surrounding articular cartilage. But the blood-injected group had similar appearance to the surrounding cartilage, with the margin of the defect barely discerptible. Strong S-100 stained immune cartilage cells were observed in the blood-injected group. CONCLUSION: The repairing process of the injured articular cartilage using autologous blood was shown to be much better than that of saline-injected group although the observation period was short and the number of animal was small. So we found that autologous blood effectively repaired osteochondral defects.
Palabras clave
Texto completo:
1
Banco de datos:
WPRIM
Asunto principal:
Rótula
/
Cartílago
/
Cartílago Articular
/
Glucosa
/
Rodilla
Límite:
Animals
Idioma:
Ko
Revista:
Journal of the Korean Academy of Rehabilitation Medicine
Año:
2005
Tipo del documento:
Article