Progress of microglial targeting PET imaging on translocator protein in Parkinson′s disease / 中华核医学与分子影像杂志
Chinese Journal of Nuclear Medicine and Molecular Imaging
; (6): 560-563, 2018.
Article
en Zh
| WPRIM
| ID: wpr-807176
Biblioteca responsable:
WPRO
ABSTRACT
Neuroinflammation has been a key pathological process in many neurodegenerative disorders including Parkinson′s disease (PD), while the microglial activation is not only involved in but also regarded as a hallmark of the neuroinflammation. With PET, it has become possible to image in vivo the changes of microglia cells under different pathophysiological conditions. In this review, the basic theory of translocator protein (TSPO)-targeting PET (TSPO-PET) imaging is well described and its intriguing applications in PD are also elaborated.
Texto completo:
1
Banco de datos:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Nuclear Medicine and Molecular Imaging
Año:
2018
Tipo del documento:
Article