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1.
Site-Specific Conjugation of the Indolinobenzodiazepine DGN549 to Antibodies Affords Antibody-Drug Conjugates with an Improved Therapeutic Index as Compared with Lysine Conjugation.
Bioconjug Chem;
31(1): 93-103, 2020 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31747250
2.
A CD123-targeting antibody-drug conjugate, IMGN632, designed to eradicate AML while sparing normal bone marrow cells.
Blood Adv;
2(8): 848-858, 2018 04 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-29661755
3.
Dual Inhibition of IGF-1R and ErbB3 Enhances the Activity of Gemcitabine and Nab-Paclitaxel in Preclinical Models of Pancreatic Cancer.
Clin Cancer Res;
24(12): 2873-2885, 2018 06 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29549161
4.
IMGN779, a Novel CD33-Targeting Antibody-Drug Conjugate with DNA-Alkylating Activity, Exhibits Potent Antitumor Activity in Models of AML.
Mol Cancer Ther;
17(6): 1271-1279, 2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29588393
5.
MM-141, an IGF-IR- and ErbB3-directed bispecific antibody, overcomes network adaptations that limit activity of IGF-IR inhibitors.
Mol Cancer Ther;
13(2): 410-25, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24282274
6.
Antitumor activity of a novel bispecific antibody that targets the ErbB2/ErbB3 oncogenic unit and inhibits heregulin-induced activation of ErbB3.
Mol Cancer Ther;
11(3): 582-93, 2012 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-22248472
7.
PT-100, a small molecule dipeptidyl peptidase inhibitor, has potent antitumor effects and augments antibody-mediated cytotoxicity via a novel immune mechanism.
Cancer Res;
64(15): 5471-80, 2004 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15289357
8.
Hematopoietic stimulation by a dipeptidyl peptidase inhibitor reveals a novel regulatory mechanism and therapeutic treatment for blood cell deficiencies.
Blood;
102(5): 1641-8, 2003 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-12738665
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