Búsqueda | Portal Regional de la BVS Paraguay

1.

Separating the Wheat from the Chaff.

Agur, Zvia.

Isr Med Assoc J; 24(11): 705-707, 2022 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-36436035

2.

Developing and validating a machine learning prognostic model for alerting to imminent deterioration of hospitalized patients with COVID-19.

Kogan, Yuri; Robinson, Ari; Itelman, Edward; Bar-Nur, Yeonatan; Jakobson, Daniel Jorge; Segal, Gad; Agur, Zvia.

Sci Rep; 12(1): 19220, 2022 11 10.

Artículo en Inglés | MEDLINE | ID: mdl-36357439

3.

A New Method for Optimizing Sepsis Therapy by Nivolumab and Meropenem Combination: Importance of Early Intervention and CTL Reinvigoration Rate as a Response Marker.

Gillis, Avi; Ben Yaacov, Anat; Agur, Zvia.

Front Immunol; 12: 616881, 2021.

Artículo en Inglés | MEDLINE | ID: mdl-33732241

4.

Accelerating the Development of Personalized Cancer Immunotherapy by Integrating Molecular Patients' Profiles with Dynamic Mathematical Models.

Agur, Zvia; Elishmereni, Moran; Forys, Urszula; Kogan, Yuri.

Clin Pharmacol Ther; 108(3): 515-527, 2020 09.

Artículo en Inglés | MEDLINE | ID: mdl-32535891

5.

Predicting response to pembrolizumab in metastatic melanoma by a new personalization algorithm.

Tsur, Neta; Kogan, Yuri; Avizov-Khodak, Evgenia; Vaeth, Désirée; Vogler, Nils; Utikal, Jochen; Lotem, Michal; Agur, Zvia.

J Transl Med; 17(1): 338, 2019 10 07.

Artículo en Inglés | MEDLINE | ID: mdl-31590677

6.

Alleviation of exhaustion-induced immunosuppression and sepsis by immune checkpoint blockers sequentially administered with antibiotics-analysis of a new mathematical model.

Gillis, Avi; Beil, Michael; Halevi-Tobias, Karin; van Heerden, Peter Vernon; Sviri, Sigal; Agur, Zvia.

Intensive Care Med Exp; 7(1): 32, 2019 Jun 11.

Artículo en Inglés | MEDLINE | ID: mdl-31187301

7.

Extracellular inhibitors can attenuate tumorigenic Wnt pathway activity in adenomatous polyposis coli mutants: Predictions of a validated mathematical model.

Hochman, Gili; Halevi-Tobias, Karin; Kogan, Yuri; Agur, Zvia.

PLoS One; 12(7): e0179888, 2017.

Artículo en Inglés | MEDLINE | ID: mdl-28708837

8.

Employing dynamical computational models for personalizing cancer immunotherapy.

Agur, Zvia; Halevi-Tobias, Karin; Kogan, Yuri; Shlagman, Ofer.

Expert Opin Biol Ther; 16(11): 1373-1385, 2016 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-27564141

9.

Predicting time to castration resistance in hormone sensitive prostate cancer by a personalization algorithm based on a mechanistic model integrating patient data.

Elishmereni, Moran; Kheifetz, Yuri; Shukrun, Ilan; Bevan, Graham H; Nandy, Debashis; McKenzie, Kyle M; Kohli, Manish; Agur, Zvia.

Prostate; 76(1): 48-57, 2016 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-26419619

10.

Complex pattern of interleukin-11-induced inflammation revealed by mathematically modeling the dynamics of C-reactive protein.

Kheifetz, Yuri; Elishmereni, Moran; Agur, Zvia.

J Pharmacokinet Pharmacodyn; 41(5): 479-91, 2014 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-25231819

11.

The resonance phenomenon in population persistence: can the same theory guide both national security policies and personalized medicine?

Agur, Zvia.

Croat Med J; 55(2): 93-102, 2014 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-24778095

12.

Personalizing oncology treatments by predicting drug efficacy, side-effects, and improved therapy: mathematics, statistics, and their integration.

Agur, Zvia; Elishmereni, Moran; Kheifetz, Yuri.

Wiley Interdiscip Rev Syst Biol Med; 6(3): 239-53, 2014.

Artículo en Inglés | MEDLINE | ID: mdl-24604755

13.

Personalizing immunotherapy: Balancing predictability and precision.

Agur, Zvia; Vuk-Pavlovic, Stanimir.

Oncoimmunology; 1(7): 1169-1171, 2012 Oct 01.

Artículo en Inglés | MEDLINE | ID: mdl-23170268

14.

Analyzing transformation of myelodysplastic syndrome to secondary acute myeloid leukemia using a large patient database.

Shukron, Ofir; Vainstein, Vladimir; Kündgen, Andrea; Germing, Ulrich; Agur, Zvia.

Am J Hematol; 87(9): 853-60, 2012 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-22674538

15.

Reconsidering the paradigm of cancer immunotherapy by computationally aided real-time personalization.

Kogan, Yuri; Halevi-Tobias, Karin; Elishmereni, Moran; Vuk-Pavlovic, Stanimir; Agur, Zvia.

Cancer Res; 72(9): 2218-27, 2012 May 01.

Artículo en Inglés | MEDLINE | ID: mdl-22422938

16.

A new validated mathematical model of the Wnt signalling pathway predicts effective combinational therapy by sFRP and Dkk.

Kogan, Yuri; Halevi-Tobias, Karin E; Hochman, Gili; Baczmanska, Anna K; Leyns, Luc; Agur, Zvia.

Biochem J; 444(1): 115-25, 2012 May 15.

Artículo en Inglés | MEDLINE | ID: mdl-22356261

17.

Mathematical modeling in immunotherapy of cancer: personalizing clinical trials.

Agur, Zvia; Vuk-Pavlovic, Stanimir.

Mol Ther; 20(1): 1-2, 2012 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-22215048

18.

Strategies for cancer stem cell elimination: insights from mathematical modeling.

Vainstein, Vladimir; Kirnasovsky, Oleg U; Kogan, Yuri; Agur, Zvia.

J Theor Biol; 298: 32-41, 2012 Apr 07.

Artículo en Inglés | MEDLINE | ID: mdl-22210402

19.

An integrated disease/pharmacokinetic/pharmacodynamic model suggests improved interleukin-21 regimens validated prospectively for mouse solid cancers.

Elishmereni, Moran; Kheifetz, Yuri; Søndergaard, Henrik; Overgaard, Rune Viig; Agur, Zvia.

PLoS Comput Biol; 7(9): e1002206, 2011 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-22022259

20.

Dickkopf1 regulates fate decision and drives breast cancer stem cells to differentiation: an experimentally supported mathematical model.

Agur, Zvia; Kirnasovsky, Oleg U; Vasserman, Genadiy; Tencer-Hershkowicz, Lilach; Kogan, Yuri; Harrison, Hannah; Lamb, Rebecca; Clarke, Robert B.

PLoS One; 6(9): e24225, 2011.

Artículo en Inglés | MEDLINE | ID: mdl-21915302

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