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1.
Cureus ; 15(9): e45391, 2023 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-37724096

RESUMEN

Granulomatous rosacea is a chronic inflammatory skin disease. We present the case of a 30-year-old woman with a three-month history of erythematous monomorphic papules and nodules on the cheeks and forehead. Histopathological examinations revealed tuberculoid granulomas with multinucleated giant cells. Granulomatous rosacea should be differentiated from other similar granulomatous skin diseases such as cutaneous sarcoidosis and Lupus miliaris disseminates faciei.

2.
J Korean Med Sci ; 37(5): e32, 2022 Feb 07.
Artículo en Inglés | MEDLINE | ID: mdl-35132838

RESUMEN

Dermatomyositis (DM) is one of the uncommon multi-organ idiopathic inflammatory myopathies that has been reported following the hepatitis B, Influenza, tetanus toxoid, H1N1, and BCG vaccines. However, an association with the coronavirus disease 2019 (COVID-19) vaccine is yet to be reported. In this case, we present the case of a 43-year-old Asian Indian female who was diagnosed with DM 10 days after receiving the second dosage of BNT162b2 mRNA COVID-19 vaccination, in the absence of any additional triggering factors. The diagnosis was established based on physical examination, serological antibodies, magnetic resonance imaging of the muscles, skin biopsy, and electromyography. She received standard treatment for DM, including oral high doses of prednisolone, hydroxychloroquine, mycophenolate, and physiotherapy. The treatment successfully reversed skin changes and muscle weakness. This is the first reported case of classic DM complicated by interstitial lung disease following COVID-19 vaccination. More clinical and functional studies are needed to elucidate this association. Clinicians should be aware of this unexpected adverse event following COVID-19 vaccination and arrange for appropriate management.


Asunto(s)
Vacuna BNT162/efectos adversos , Dermatomiositis/diagnóstico , Adulto , Vacuna BNT162/administración & dosificación , COVID-19/prevención & control , COVID-19/virología , Dermatomiositis/etiología , Electromiografía , Femenino , Humanos , Enfermedades Pulmonares Intersticiales/diagnóstico , Enfermedades Pulmonares Intersticiales/etiología , Imagen por Resonancia Magnética , Músculo Esquelético/diagnóstico por imagen , SARS-CoV-2/aislamiento & purificación , Piel/patología , Vacunación/efectos adversos
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