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1.
Tumour-selective antivascular effects of the novel anti-mitotic compound A-318315: An in vivo rat regional haemodynamic study.
Clin Exp Pharmacol Physiol;
37(5-6): 636-40, 2010 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-20132238
2.
ABT-888, an orally active poly(ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor models.
Clin Cancer Res;
13(9): 2728-37, 2007 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17473206
3.
Discovery of N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)urea (ABT-869), a 3-aminoindazole-based orally active multitargeted receptor tyrosine kinase inhibitor.
J Med Chem;
50(7): 1584-97, 2007 Apr 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-17343372
4.
Discovery of trans-3,4'-bispyridinylethylenes as potent and novel inhibitors of protein kinase B (PKB/Akt) for the treatment of cancer: Synthesis and biological evaluation.
Bioorg Med Chem Lett;
16(6): 1679-85, 2006 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-16403626
5.
Thienopyrimidine ureas as novel and potent multitargeted receptor tyrosine kinase inhibitors.
J Med Chem;
48(19): 6066-83, 2005 Sep 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-16162008
6.
Synthesis of 1H-pyridin-2-one derivatives as potent and selective farnesyltransferase inhibitors.
Bioorg Med Chem Lett;
14(18): 4603-6, 2004 Sep 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-15324873
7.
Tumor selective antivascular effects of the novel antimitotic compound ABT-751: an in vivo rat regional hemodynamic study.
Cancer Chemother Pharmacol;
54(3): 273-81, 2004 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-15173957
8.
Design, synthesis, and biological activity of 4-[(4-cyano-2-arylbenzyloxy)-(3-methyl-3H-imidazol-4-yl)methyl]benzonitriles as potent and selective farnesyltransferase inhibitors.
J Med Chem;
47(3): 612-26, 2004 Jan 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-14736242
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