Echographic follow up of malignant melanoma of the choroid after brachytherapy with iodine-125.

A 52-year-old male patient is presented. The patient was referred to our service for a pigmented tumor of the inferonasal quadrant of retina in OD. Fundus examination confirmed a pigmented tumor of 3 DD, elevated and dome shaped. Ultrasonography showed a dome shaped lesion of 6.3 mm at the base and 3.29 mm in height, medium internal reflectivity and positive for vascularity. Clinical diagnosis of choroidal melanoma was made and brachytherapy with iodine-125 was performed. Findings recorded at 3-year ultrasonographic follow up are discussed.

[Coat's disease treated with bevacizumab (Avastin)]. / Enfermedad de coats tratada con bevacizumab (Avastin).

CASE REPORT: We report a case of Coats' disease in a 10-year-old-girl who presented with a profound visual deficit, exudative retinal detachment, vascular telangiectasias and subretinal lipid, who underwent treatment with an intravitreal injection of bevacizumab (AVASTIN(TM)). Serial examinations documented an involutional response with a reduction of the subretinal fluid, exudates and macular thickness. DISCUSSION: The aetiology of Coats' disease remains uncertain, as does its optimal management. Although resolution of a case depends partially on age, and can even occur spontaneously on rare occasions, intravitreal injections of bevacizumab should be considered when planning treatment.

[Macular hole surgery without postoperatory <> down positioning. Pilot study]. / Cirugía de agujero macular sin posición <> postoperatoria. Estudio piloto.

PURPOSE: To evaluate the visual and anatomical outcomes of macular hole surgery using phacoemulsification, vitrectomy and intraocular gas tamponade without the use of postoperative face down positioning. METHODS: Phacoemulsification with an intraocular lens implant, followed by vitrectomy with internal limiting membrane peeling and perfluoropropane (C3F8), was performed in patients with stage 3 or 4 macular holes. After surgery, patients had to avoid the supine position for 15 days. Patients with a gas level <50% during the first week had a fluid-gas exchange. Visual acuity and closure of the macular hole were evaluated after 1 year of follow-up. RESULTS: 20 eyes of 20 patients, aged 60 to 75 years (median age 68 years), were included in this study. The best initial visual acuity ranged from 0.05 to 0.13 (ETDRS), with the median being 0.06. The final visual acuity was 0.05 to 0.30 with a median of 0.10. A statistically significant improvement (p=0.001, Wilcoxon) was found. The anatomic postoperative results revealed 90% (n=18) of the macular holes were closed while 10% (n=2) were not. CONCLUSIONS: Macular hole surgery has, in general, good results and patients can achieve improvement in their visual acuity without the need for uncomfortable and unbearable post operative posture positions.