Sindrome febril y fiebre de origen desconocido (II) / Febrile syndrome and fever of unknown origin )II

Se continua con la revisión del tema fiebre de origen desconocido. Se exponen las características de la fiebre en el anciano y en la embarazada. Se caracterizan las principales causas de fod, haciendo enfasis en las infecciones, las neoplasias y las enfermedades conectivo-vasculares

Sindrome febril y fiebre de orÍgen desconocido (III) / Febrile syndrome and fever of origen stranger (III)

Con este artículo se da fin a la trilogia que sobre el sindrome febril y fiebre de orÍgen desconocido había comenzado a publicar nuestra revista. Esta tercera parte esta dedicada al protocolo que se sugiere debe seguirse para el diagnóstico de la fod, se hace especial énfasis en los exámenes paraclínicos que contribuyen al diagnóstico, señalando sus características particulares, utilidad e indicaciones

Detection by ELISA of specific IgG to mycobacterial antigen 60 in a tuberculous exudate.

A case of active multicavitary tuberculosis is reported. In the 3rd month of treatment, an X-ray film of the thorax showed right pleural effusion. The properties of the pleural fluid were those of an exudate with high adenosine deaminase activity. An ELISA was performed to detect specific IgG antibody to mycobacterial antigen 60 in serum before the treatment and on a two-monthly basis following the initiation of therapy until completion of the course. Values were all above 1,750 U. Moreover, an ELISA test using the same antigen was done on pleural fluid, and a high IgG titer was obtained (950 U). A cutoff for a positive ELISA test was established at 240 U in serum and 150 U in other biologic fluids.

[Sweet syndrome: presentation of an atypical case and review of the literature]. / Síndrome de Sweet: presentación de un caso atípico y revisión de la literatura.

In 1964 Sweet described a new syndrome which was characterized by pyrexia, neutrophilia, and the abrupt appearance of erythematous, painful, cutaneous plaques, primarily on the upper extremities, head, and neck. Histologically, the prominent feature is a dense dermal infiltrate of neutrophils, without signs of vasculitis, with a prompt response to steroid therapy. Since then up to 150 cases have been reported, being actually considered an immune mechanism responsible of this syndrome and we now have criterions for the diagnosis of it. We report a patient with Sweet's syndrome (SS): who has all the diagnostic criterions, whose main interest is having suffered from erythema nodosum three years before; this is the second case we have found in the English literature, and we also discuss some peculiarities.