RESUMEN
We report a case of infection with New York orthohantavirus in a woman who showed renal impairment and hemorrhage, complicated by hydrocephalus, in Long Island, New York, USA. Phylogenetic analysis showed that this virus was genetically similar to a New York orthohantavirus isolated in the same region during 1993.
Asunto(s)
Infecciones por Hantavirus/diagnóstico , Infecciones por Hantavirus/virología , Hidrocefalia/diagnóstico , Orthohantavirus , Insuficiencia Respiratoria/diagnóstico , Biomarcadores , Femenino , Orthohantavirus/clasificación , Orthohantavirus/genética , Orthohantavirus/inmunología , Orthohantavirus/aislamiento & purificación , Infecciones por Hantavirus/complicaciones , Secuenciación de Nucleótidos de Alto Rendimiento , Humanos , Hidrocefalia/etiología , Hemorragias Intracraneales/diagnóstico , Hemorragias Intracraneales/etiología , Persona de Mediana Edad , ARN Viral , Insuficiencia Respiratoria/etiología , Pruebas Serológicas , Evaluación de SíntomasRESUMEN
Patients with epilepsy are at risk of traffic accidents when they have seizures while driving. However, driving is an essential part of normal daily life in many communities, and depriving patients of driving privileges can have profound consequences for their economic and social well-being. In the current study, we collected ictal performance data from a driving simulator and two other video games in patients undergoing continuous video/EEG monitoring. We captured 22 seizures in 13 patients and found that driving impairment during seizures differed in terms of both magnitude and character, depending on the seizure type. Our study documents the feasibility of a prospective study of driving and other behaviors during seizures through the use of computer-based tasks. This methodology may be applied to further describe differential driving impairment in specific types of seizures and to gain data on anatomical networks disrupted in seizures that impair consciousness and driving safety.
Asunto(s)
Conducción de Automóvil , Epilepsia/complicaciones , Inconsciencia/etiología , Inconsciencia/rehabilitación , Interfaz Usuario-Computador , Juegos de Video , Adolescente , Adulto , Niño , Diseño Asistido por Computadora , Evaluación de la Discapacidad , Electroencefalografía/métodos , Epilepsia/clasificación , Epilepsia/rehabilitación , Estudios de Factibilidad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Desempeño Psicomotor , Grabación en Video , Adulto JovenRESUMEN
CONTEXT: A broad spectrum of nonneoplastic conditions can mimic a brain tumor, both clinically and radiologically. In this review we consider these, taking into consideration the following etiologic categories: infection, demyelination, vascular diseases, noninfectious inflammatory disorders, and iatrogenic conditions. We give an overview of such diseases, which represent a potential pitfall for pathologists and other clinicians involved in patient care, and present selected cases from each category. OBJECTIVE: To illustrate the radiologic and pathologic features of nontumoral intracranial lesions that can clinically and radiologically mimic neoplasia. DATA SOURCES: Case-derived material and literature review. CONCLUSIONS: A variety of nonneoplastic lesions can present clinically and radiologically as primary or metastatic central nervous system tumors and result in surgical biopsy or resection of the lesion. In such situations, the pathologist has an important role to play in correctly determining the nature of these lesions. Awareness of the entities that can present in this way will assist the pathologist in the correct diagnosis of these lesions.