Efficient removal of metal ions from aqueous solutions using MoS2 functionalized chitosan Schiff base incorporated with Fe3O4 nanoparticle.

In the present work a novel pyrazole based chitosan Schiff base material was prepared using 5-azido-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde and functionalized using Fe3O4-MoS2, where the nanoparticles get embedded within the gel matrix. The composite material was characterized using various techniques such as XRD, SEM, FTIR, EDS and TGA. The adsorbent material was analysed for the adsorptive take up process from the aqueous solutions of metal ion concentration ranging 20-100 mgL-1. The maximum adsorption capacity obtained for the material was 200.00 and 125.00 mg/g for Cr(VI) and Cu(II) respectively. Adsorptive mechanism was found to have pseudo second order kinetics and the adsorption isotherm followed Langmuir adsorption model following the monolayer adsorptive process. Further the evaluated thermodynamic parameter showed the adsorption process to be spontaneous and endothermic in nature. Reusability of the composite material was achieved using suitable stripping solutions.

Antibacterial activities of sulfonyl or sulfonamide containing heterocyclic derivatives and its structure-activity relationships (SAR) studies: A critical review.

The rise of drug-resistance has made the deserted clinical requirement to improve of new classes of antibiotics agents. The development of antibacterial agents with the novel method of activity stays a high need worldwide. The treatment of bacterial infections remains a test in light of developing irresistible sicknesses and the expanding number of multidrug-resistance microbial pathogens. Therefore, there is a need for powerful activities to think of new successful therapeutic agents, and it is dire to find novel synthetic analogs against bacterial targets. The improvements of new, less harmful, minimum side-effort, and extremely dynamic sulfonyl or sulfonamide-bearing analogs are hot research topics in medicinal chemistry. This present review summarizes the current innovations of sulfonyl or sulfonamide-based derivatives with potential antibacterial activities against various Gram-positive and Gram-negative bacterial strains and discussing its various aspects of structure-activity relationship (SAR).