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1.
J Psychiatr Ment Health Nurs ; 24(6): 358-366, 2017 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-28218977

RESUMEN

WHAT IS KNOWN ON THE SUBJECT?: There is consistent evidence that service users and carers feel marginalized in the process of mental health care planning. Mental health professionals have identified ongoing training needs in relation to involving service users and carers in care planning. There is limited research on the acceptability of training packages for mental health professionals which involve service users and carers as co-facilitators. WHAT DOES THIS PAPER ADD TO EXISTING KNOWLEDGE?: A co-produced and co-delivered training package on service user- and carer-involved care planning was acceptable to mental health professionals. Aspects of the training that were particularly valued were the co-production model, small group discussion and the opportunity for reflective practice. The organizational context of care planning may need more consideration in future training models. WHAT ARE THE IMPLICATIONS FOR PRACTICE?: Mental health nurses using co-production models of delivering training to other mental health professionals can be confident that such initiatives will be warmly welcomed, acceptable and engaging. On the basis of the results reported here, we encourage mental health nurses to use co-production approaches more often. Further research will show how clinically effective this training is in improving outcomes for service users and carers. ABSTRACT: Background There is limited evidence for the acceptability of training for mental health professionals on service user- and carer-involved care planning. Aim To investigate the acceptability of a co-delivered, two-day training intervention on service user- and carer-involved care planning. Methods Community mental health professionals were invited to complete the Training Acceptability Rating Scale post-training. Responses to the quantitative items were summarized using descriptive statistics (Miles, ), and qualitative responses were coded using content analysis (Weber, ). Results Of 350 trainees, 310 completed the questionnaire. The trainees rated the training favourably (median overall TARS scores = 56/63; median 'acceptability' score = 34/36; median 'perceived impact' score = 22/27). There were six qualitative themes: the value of the co-production model; time to reflect on practice; delivery preferences; comprehensiveness of content; need to consider organizational context; and emotional response. Discussion The training was found to be acceptable and comprehensive with participants valuing the co-production model. Individual differences were apparent in terms of delivery preferences and emotional reactions. There may be a need to further address the organizational context of care planning in future training. Implications for practice Mental health nurses should use co-production models of continuing professional development training that involve service users and carers as co-facilitators.


Asunto(s)
Cuidadores , Servicios Comunitarios de Salud Mental , Personal de Salud/educación , Trastornos Mentales/terapia , Planificación de Atención al Paciente , Adulto , Humanos
2.
J Psychiatr Ment Health Nurs ; 24(6): 367-376, 2017 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-28105690

RESUMEN

WHAT IS KNOWN ON THE SUBJECT?: UK NHS policy highlights the importance of user and carer involvement in health professional training. We know little about service user and carer motivations and experiences of accessing training courses for delivering training to health professionals and how well such courses prepare them for delivering training to healthcare professionals. 'Involvement' in training has often been tokenistic and too narrowly focused on preregistration courses. There is limited data on how best to prepare and support potential service user and carer trainers. WHAT DOES THIS PAPER ADD TO EXISTING KNOWLEDGE?: This study adds to the international literature by highlighting service user and carer motivations for accessing a training course for delivering training to health professionals. Service users and carers wanted to gain new skills and confidence in presentation/facilitation as well as to make a difference to healthcare practice. We also learned that service users desired different levels of involvement in training facilitation - some wanted to take a more active role than others. A one-size-fits-all approach is not always appropriate. Encountering resistance from staff in training was a previously unidentified challenge to service user and carers' experience of delivering training in practice and is a key challenge for trainers to address in future. Professional training involvement can be enhanced via specialist training such as the EQUIP training the trainers programme evaluated here. WHAT ARE THE IMPLICATIONS FOR PRACTICE?: When training service users and carers to deliver training to mental health professionals, it is important that service users are equipped to deal with resistance from staff. It is important that service user and carer roles are negotiated and agreed prior to delivering training to healthcare professionals to accommodate individual preferences and allay anxieties. Training for service users and carers must be offered alongside ongoing support and supervision. Mental health nurses (and other health professionals) will be better able to involve service users and carers in care planning. Service users and carers may feel more involved in care planning in future. ABSTRACT: Introduction Limited evidence exists on service user and carer perceptions of undertaking a training course for delivering care planning training to qualified mental health professionals. We know little about trainee motivations for engaging with such train the trainers courses, experiences of attending courses and trainees' subsequent experiences of codelivering training to health professionals, hence the current study. Aim To obtain participants' views on the suitability and acceptability of a training programme that aimed to prepare service users and carers to codeliver training to health professionals. Method Semi-structured interviews with nine service users and carers attending the training programme. Transcripts were analysed using inductive thematic analysis. Results Participants' reasons for attending training included skill development and making a difference to mental health practice. Course content was generally rated highly but may benefit from review and/or extension to allow the range of topics and resulting professional training programme to be covered in more depth. Trainees who delivered the care planning training reported a mix of expectations, support experiences, preparedness and personal impacts. Implications for Practice Mental health nurses are increasingly coproducing and delivering training with service users and carers. This study identifies possibilities and pitfalls in this endeavour, highlighting areas where user and carer involvement and support structures might be improved in order to fully realize the potential for involvement in training.


Asunto(s)
Cuidadores , Personal de Salud/educación , Servicios de Salud Mental , Planificación de Atención al Paciente , Pacientes , Evaluación de Programas y Proyectos de Salud , Adulto , Humanos
3.
J Psychiatr Ment Health Nurs ; 23(1): 12-21, 2016 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-26634415

RESUMEN

BACKGROUND: Service users wish to be involved in care planning but typically feel marginalized in this process. Qualitative explorations of the barriers and enablers of user involvement in mental health care planning are limited. QUESTION: How is user involvement in care planning conceptualized by service users and how can meaningful involvement be instilled in the care planning process? METHODS: In 2013, we conducted five focus groups (n = 27) and 23 individual interviews with current or recent adult users of secondary care mental health services (n = 27) in England. Eight users participated in both. Data were analysed using Framework Analysis. Results Ten themes emerged from the data: these themes encompassed procedural elements (connection; contribution; currency; care consolidation; and consequence), service user characteristics (capacity and confidence) and professional enablers (consultation; choice; and clarity of expression). Procedural elements were discussed most frequently in service user discourse. DISCUSSION: The process of care planning, centred on the user-clinician relationship, is key to user involvement. IMPLICATIONS FOR PRACTICE: Users describe a common model of meaningful involvement in care planning. Their requests, summarized through a 10C framework of care planning involvement, provide clear direction for improving service users satisfaction with care planning and enhancing the culture of services.


Asunto(s)
Servicios de Salud Mental , Planificación de Atención al Paciente , Participación del Paciente , Relaciones Profesional-Paciente , Investigación Cualitativa , Adulto , Humanos
4.
Med Hypotheses ; 77(3): 430-6, 2011 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-21723672

RESUMEN

Shift work has been associated with various adverse health outcomes. In particular, there has been a recent flourish in investigating potential cancer risk associated with working night shifts and other shift schedules. Epidemiologic studies have revealed generally weak associations due to several methodological challenges such as lack of standard classifications of shift or night work. The field also has been hindered by a lack of clarity about the possible mechanisms by which shiftwork could have an effect on cancer risk. One possible mechanism is reduced production of melatonin caused by exposure to light at night. Although there is a growing body of evidence that provides some support for this mechanism, several other mechanisms also make sense from a biological point of view. Further, the relatively weak magnitude of the associations between light at night and melatonin level suggests that multiple factors may be operating along the pathway between shift work and adverse health consequences (including cancer risk). Here we propose four additional mechanisms that should be considered for a comprehensive investigation of these potential pathways. These are: phase shift; sleep disruption; lifestyle factors (such as poor quality diets, less physical activity and higher BMI); and lower vitamin D. Consideration of all these mechanisms is necessary in order to design effective preventative workplace strategies. In developed countries, approximately 20% of the population undertake shiftwork and, while we are unlikely to be able to eliminate shiftwork from current work practices, there are aspects of shiftwork that can be modified and there may be facets of individual susceptibility that we may be able to identify and target for prevention.


Asunto(s)
Melatonina/metabolismo , Modelos Biológicos , Neoplasias/etiología , Privación de Sueño/complicaciones , Deficiencia de Vitamina D/complicaciones , Tolerancia al Trabajo Programado/fisiología , Humanos , Estilo de Vida , Luz , Factores de Riesgo
5.
J Laryngol Otol ; 124(2): 175-9, 2010 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-19840423

RESUMEN

OBJECTIVE: To assess the efficacy of radiologically guided balloon dilatation for the treatment of dysphagia secondary to neopharyngeal strictures in patients who have undergone laryngectomy. STUDY DESIGN: Retrospective case series. SUBJECTS AND METHODS: Twenty consecutive patients with pharyngeal stricture and dysphagia following total laryngectomy or pharyngolaryngectomy. Patients underwent balloon dilatation of the stricture under radiological guidance. The main outcome measure was maintenance of swallowing. RESULTS: Five patients gained relief of their dysphagia with one balloon dilatation only. Nine patients required more than one dilatation to maintain swallowing. Two patients had balloon dilatation procedures and stent insertion for palliative relief of dysphagia from known recurrent malignant disease. Three patients failed to maintain swallowing with repeat dilatations. No patients suffered any significant complications such as perforation. CONCLUSIONS: Radiologically guided balloon dilatation is minimally invasive and safe. It is well tolerated. It may be repeated frequently, and can successfully relieve pharyngeal strictures in patients who have undergone total laryngectomy or pharyngolaryngectomy.


Asunto(s)
Cateterismo/métodos , Trastornos de Deglución/terapia , Laringectomía/efectos adversos , Enfermedades Faríngeas/terapia , Faringectomía/efectos adversos , Complicaciones Posoperatorias/terapia , Adulto , Anciano , Anciano de 80 o más Años , Constricción Patológica/etiología , Constricción Patológica/terapia , Trastornos de Deglución/etiología , Femenino , Humanos , Enfermedades de la Laringe/complicaciones , Enfermedades de la Laringe/cirugía , Masculino , Persona de Mediana Edad , Enfermedades Faríngeas/complicaciones , Radiografía Intervencional/métodos
6.
Phys Rev Lett ; 101(13): 136409, 2008 Sep 26.
Artículo en Inglés | MEDLINE | ID: mdl-18851475

RESUMEN

We observe the buildup of strong (approximately 50%) spontaneous vector polarization in emission from a GaN-based polariton laser excited by short optical pulses at room temperature. The Stokes vector of emitted light changes its orientation randomly from one excitation pulse to another, so that the time-integrated polarization remains zero. This behavior is completely different from any previous laser. We interpret this observation in terms of the spontaneous symmetry breaking in a Bose-Einstein condensate of exciton polaritons.

7.
Phys Rev Lett ; 98(12): 126405, 2007 Mar 23.
Artículo en Inglés | MEDLINE | ID: mdl-17501142

RESUMEN

We observe a room-temperature low-threshold transition to a coherent polariton state in bulk GaN microcavities in the strong-coupling regime. Nonresonant pulsed optical pumping produces rapid thermalization and yields a clear emission threshold of 1 mW, corresponding to an absorbed energy density of 29 microJ cm-2, 1 order of magnitude smaller than the best optically pumped (In,Ga)N quantum-well surface-emitting lasers (VCSELs). Angular and spectrally resolved luminescence show that the polariton emission is beamed in the normal direction with an angular width of +/-5 degrees and spatial size around 5 microm.

8.
Protoplasma ; 227(1): 47-52, 2005 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-16389493

RESUMEN

The question is how long phytochrome, stored within the cytoplasm of plant diaspores, may stimulate their germination. This question arose from the observation that soil cultivations in darkness for weed control gave inconsistent results. Namely, after a single nighttime or daytime cultivation during spring and summer, differences in weed emergence became hardly detectable after a period of six weeks. However, after nighttime and daytime cultivations in late autumn, emergence differences persisted for up to nine months. To examine whether this differing memory effect is phytochrome-mediated, seeds of Chenopodium album and Stellaria media were sown in pots with wet peat, either in daylight or after sunset. In the latter, seeds were irradiated with far-red light for one day prior to being covered and buried. For more than two years the far-red irradiated seeds produced significantly reduced emergence, indicating that germination and emergence of weeds in the field may be supported by maternal far-red absorbing seed phytochrome B(fr) over several months or even years. This conclusion allows refining of the strategy of lightless tillage.


Asunto(s)
Chenopodium album/crecimiento & desarrollo , Fitocromo/fisiología , Semillas , Stellaria/crecimiento & desarrollo , Chenopodium album/efectos de la radiación , Germinación/efectos de la radiación , Luz , Memoria , Stellaria/efectos de la radiación
9.
Br J Radiol ; 77(916): 323-8, 2004 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-15107323

RESUMEN

This study validates a method to add spatially correlated statistical noise to an image, applied to transaxial X-ray CT images of the head to simulate exposure reduction by up to 50%. 23 patients undergoing routine head CT had three additional slices acquired for validation purposes, two at the same clinical 420 mAs exposure and one at 300 mAs. Images at the level of the cerebrospinal fluid filled ventricles gave readings of noise from a single image, with subtraction of image pairs to obtain noise readings from non-uniform tissue regions. The spatial correlation of the noise was determined and added to the acquired 420 mAs image to simulate images at 340 mAs, 300 mAs, 260 mAs and 210 mAs. Two radiologists assessed the images, finding little difference between the 300 mAs simulated and acquired images. The presence of periventricular low density lesions (PVLD) was used as an example of the effect of simulated dose reduction on diagnostic accuracy, and visualization of the internal capsule was used as a measure of image quality. Diagnostic accuracy for the diagnosis of PVLD did not fall significantly even down to 210 mAs, though visualization of the internal capsule was poorer at lower exposure. Further work is needed to investigate means of measuring statistical noise without the need for uniform tissue areas, or image pairs. This technique has been shown to allow sufficiently accurate simulation of dose reduction and image quality degradation, even when the statistical noise is spatially correlated.


Asunto(s)
Encefalopatías/diagnóstico por imagen , Tomografía Computarizada por Rayos X/normas , Anciano , Simulación por Computador , Humanos , Dosis de Radiación , Sensibilidad y Especificidad , Tomografía Computarizada por Rayos X/métodos
10.
Neurogastroenterol Motil ; 15(5): 515-22, 2003 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-14507351

RESUMEN

Colorectal motor activity in slow-transit idiopathic constipation has not been fully evaluated under physiological conditions. The aim of this study was to evaluate colorectal motor activity in chronic idiopathic constipation using 24-h ambulant pancolonic manometry. Ten healthy volunteers (six females) 19-31 years of age, and eight females 25-46 years of age with slow-transit idiopathic constipation were studied. Motor activity was measured using two custom-made silicone-coated catheters, each with five solid-state pressure transducers. Bowel preparation or sedation was not used. Frequency of high-amplitude propagated contractions was reduced in chronic idiopathic constipation, median 1.9/24 h vs 6/24 h (P = 0.01). Contractile frequency of low-amplitude complexes was reduced throughout the colon in slow-transit idiopathic constipation (P < 0.0001). The interval between contractile complexes was reduced in the transverse colon and splenic flexure (P < 0.0001). This study demonstrates that colonic motor activity is abnormal in slow-transit idiopathic constipation; decreased motor activity leads to a reduction in propulsion of intraluminal contents.


Asunto(s)
Colon/fisiología , Estreñimiento/fisiopatología , Monitoreo Ambulatorio/métodos , Complejo Mioeléctrico Migratorio/fisiología , Adulto , Ritmo Circadiano/fisiología , Estreñimiento/diagnóstico , Femenino , Motilidad Gastrointestinal/fisiología , Humanos , Masculino , Manometría/métodos , Persona de Mediana Edad , Monitoreo Ambulatorio/instrumentación , Estadísticas no Paramétricas
11.
Clin Radiol ; 58(8): 606-9, 2003 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-12887953

RESUMEN

AIM: The diagnostic contribution of the anteroposterior (AP) view was studied to assess whether this view could be omitted safely, thus reducing the radiation burden received by patients undergoing lumbar spine radiography. MATERIALS AND METHODS: Prospective analysis of 1030 consecutive referrals for lumbar spine radiography from general practice. RESULTS: In the majority of cases (90.5%) the AP view was non-contributory. In 4.2% the diagnosis was strengthened and it was altered in 4.6%. However, in the latter group only 1.3% of the total were considered significant alterations. These were cases of possible, but not definite, pars defects and sacroiliitis. Specific important conditions such as infection, malignancy and benign tumours were not missed on the lateral view alone, in our study population. The radiation burden is reduced by 75% by omitting the AP view. CONCLUSION: A single lateral view is an adequate examination, with the proviso that sacroiliac joint disease is not assessed on this view and some pars defects and facet joint degenerative changes may be overlooked. The radiation protection gains are considerable. A single lateral lumbar view is now our routine practice unless sacroiliitis is a specific clinical concern.


Asunto(s)
Dolor de la Región Lumbar/diagnóstico por imagen , Vértebras Lumbares/diagnóstico por imagen , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Artritis/complicaciones , Artritis/diagnóstico por imagen , Niño , Humanos , Dolor de la Región Lumbar/etiología , Persona de Mediana Edad , Estudios Prospectivos , Radiografía , Articulación Sacroiliaca/diagnóstico por imagen , Escoliosis/complicaciones , Escoliosis/diagnóstico por imagen
12.
Neurogastroenterol Motil ; 14(3): 271-8, 2002 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-12061912

RESUMEN

The pattern of colonic motor activity in healthy humans has not been fully elucidated to date. The aim of this study was to evaluate colorectal motor activity employing 24-h ambulant pancolonic manometry. Ten healthy volunteers (6F, 4M), aged 19-31 years were studied. Motor activity was measured using two custom-made silicone coated catheters, each with five solid-state pressure transducers. No bowel preparation or sedation was used. The study period was 24 h. A total of 232 h of recording was obtained. Sixty-three high amplitude propagated contractions were observed, median six per 24-h period. Low-amplitude colonic contractile activity showed regional and diurnal variations. Frequency of contraction was highest in the right colon [median 5.26 cpm (cycles per minute)], and transverse colon and splenic flexure (median 5.15 cpm). The interval between colonic motor complexes was shortest in the transverse colon and splenic flexure. This study introduces a new technique for the evaluation of colorectal motor activity. Subjects were studied in an ambulant setting in their own environment ensuring that this method of study is as physiological as possible. This study demonstrates that colonic motor activity has two main components: high amplitude propagated contractions and low amplitude colonic contractile activity.


Asunto(s)
Ritmo Circadiano/fisiología , Colon/fisiología , Monitoreo Ambulatorio/métodos , Actividad Motora/fisiología , Recto/fisiología , Adulto , Estudios de Evaluación como Asunto , Femenino , Motilidad Gastrointestinal/fisiología , Humanos , Masculino , Manometría/instrumentación , Manometría/métodos , Monitoreo Ambulatorio/instrumentación , Peristaltismo/fisiología , Estadísticas no Paramétricas
13.
New Phytol ; 148(3): 433-444, 2000 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-33863021

RESUMEN

The germination characteristics of Stellaria media (common chickweed) were investigated over a range of constant temperatures and degrees of moisture stress in order to assess the suitability of hydrothermal time as a basis for modelling germination under field conditions. Maximum percentage germination occurred over a much narrower temperature range around the optimum temperature than previously seen for cultivated crop seed. The entire final percentage germination response to temperature in water was well described by two probit curves, and this model was extended to describe the data at all water potentials at a temperature close to the optimum. The implications of the reduction in germination at nonoptimal temperatures are discussed with respect to the interpretation of germination progress curves and conditional dormancy. After adjusting for maximum percentage germination, a hydrothermal time model was found to fit the data set well within the conditions normally encountered in horticultural seedbeds. This separation of the final percentage germination presents a flexible modelling approach that allows for the different levels of dormancy typically expressed within weed populations. By contrast with many previously reported species, S. media had a synchronous germination rate within the population at any given temperature/water potential combination. This synchronous germination of at least a proportion of the population over a wide range of temperature and water potentials might have ecological significance for the opportunistic germination behaviour of this weed species.

15.
J Vasc Interv Radiol ; 10(3): 346-51, 1999 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-10102201

RESUMEN

PURPOSE: The authors describe their experience with expanding metallic stents for the palliation of malignant dysphagia. MATERIALS AND METHODS: During a 52-month period, 138 stents were inserted in 121 patients with malignant esophageal obstruction. The average age was 74 years; there were 78 men and 43 women. Data regarding the degree of initial dysphagia, presence of an esophago-respiratory fistula, effect of stent placement on swallowing ability, complications at the time of stent placement, and long-term survival were obtained. RESULTS: An improvement in dysphagia symptoms was recorded in more than 95% of patients. The average survival after stent placement was 24 weeks. Complications necessitating further intervention occurred in 26 patients. CONCLUSION: Insertion of self-expanding metallic endoprostheses for the palliation of malignant esophageal obstruction is an effective therapy that can be carried out with relative ease. Successful palliation of symptoms can be expected in more than 95% of cases.


Asunto(s)
Adenocarcinoma/cirugía , Carcinoma de Células Escamosas/cirugía , Trastornos de Deglución/cirugía , Neoplasias Esofágicas/cirugía , Cuidados Paliativos/métodos , Stents , Adenocarcinoma/complicaciones , Adenocarcinoma/diagnóstico , Anciano , Anciano de 80 o más Años , Carcinoma de Células Escamosas/complicaciones , Carcinoma de Células Escamosas/diagnóstico , Trastornos de Deglución/diagnóstico , Trastornos de Deglución/etiología , Endoscopía del Sistema Digestivo , Neoplasias Esofágicas/complicaciones , Neoplasias Esofágicas/diagnóstico , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Radiografía Torácica , Estudios Retrospectivos , Tomografía Computarizada por Rayos X , Resultado del Tratamiento
16.
Br J Surg ; 86(1): 17-28, 1999 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-10027354

RESUMEN

BACKGROUND: The development of treatment modalities for rectal cancer, including local excision, total mesorectal excision and preoperative radiotherapy, has increased the importance of accurate preoperative staging to allow the optimum treatment to be selected. METHODS: A literature review was undertaken of methods of preoperative staging of rectal carcinoma and the evidence for each was evaluated critically. RESULTS: Clinical assessment of rectal carcinoma may give an indication of fixity but is not accurate for staging. Endoanal ultrasonography, computed tomography (CT), magnetic resonance imaging (MRI), radioimmunoscintigraphy and positron emission tomography have all been used for staging. The extent of tumour spread through the bowel wall (T stage) is most accurately assessed by endoanal ultrasonography, although this technique is poor at assessing tumour extension into adjacent organs for which both CT and MRI are more accurate. No method accurately determines lymph node involvement, but endoanal ultrasonography is the best available. Liver metastases may be assessed by abdominal ultrasonography, CT, MRI and CT portography (with increasing sensitivity and cost in that order). CONCLUSION: Endoanal ultrasonography is the most effective method of local tumour staging, with the addition of either CT or MRI if adjacent organ involvement is suspected. Abdominal ultrasonography or CT is recommended for routine preoperative assessment of the liver.


Asunto(s)
Neoplasias del Recto/diagnóstico , Humanos , Imagen por Resonancia Magnética/métodos , Estadificación de Neoplasias/métodos , Cuidados Preoperatorios/métodos , Radioinmunodetección/métodos , Neoplasias del Recto/patología , Neoplasias del Recto/cirugía , Tomografía Computarizada de Emisión/métodos , Tomografía Computarizada por Rayos X/métodos
17.
Br J Surg ; 85(2): 264-6, 1998 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-9501832

RESUMEN

BACKGROUND: The use of self-expanding metal stents for palliation of malignant dysphagia is increasing. Experience in 70 patients was reviewed with respect to the value of stenting and management of the complications encountered. METHODS: Oesophageal stents were inserted in 70 patients (42 men) of mean age 73 years with malignant oesophageal obstruction. Data regarding stent insertion and degree of dysphagia were gathered prospectively. RESULTS: Seventy-six stents were placed in 70 patients. By the end of the study 57 patients had died and 13 were still alive. Three patients died within 3 days of stent insertion and dysphagia was relieved in 64 of the 67 patients remaining. Stent migration, tumour ingrowth and overgrowth, and food impaction were encountered during follow-up in eight patients. CONCLUSION: Insertion of self-expanding metal stents for the palliation of malignant oesophageal obstruction is a successful therapy which can be carried out with relative ease. Palliation of dysphagia with an appropriate stent can be expected in up to 95 per cent of patients.


Asunto(s)
Neoplasias Esofágicas/cirugía , Estenosis Esofágica/cirugía , Stents , Anciano , Anciano de 80 o más Años , Trastornos de Deglución/etiología , Trastornos de Deglución/cirugía , Contaminación de Equipos , Femenino , Estudios de Seguimiento , Migración de Cuerpo Extraño , Humanos , Masculino , Persona de Mediana Edad , Recurrencia Local de Neoplasia , Cuidados Paliativos/métodos , Estudios Prospectivos , Recurrencia , Resultado del Tratamiento
19.
Dig Dis Sci ; 40(9): 1956-62, 1995 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-7555450

RESUMEN

The aim of the study was to assess the value of quantitative attenuation values (Hounsfield units) and of gallstone pattern by computerized tomography in predicting response to bile acid therapy. We carried out a prospective study in a multicenter setting on 90 consecutive outpatients with radiolucent gallstones. All received bile acid therapy (UDCA 10 mg/kg/day or UDCA + CDCA 5 mg/kg/day of each) up to two years. Hounsfield units for gallstones were recorded using standardized criteria and six categories of patterns were defined: hypodense, isodense, homogenously dense, laminated, rimmed and speckled. We assessed gallstone dissolution rate (percent reduction in volume), response to therapy (> 25% reduction in volume), and final outcome of therapy. Eighty-one percent of patients with hypodense/isodense and all four patients with speckled stone pattern responded to therapy, whereas none of the 10 patients with laminated/rimmed and only 45% of patients with homogenously dense stone pattern did. Complete dissolution was achieved by 68%, 50%, 35%, 0% of the hypodense/isodense, speckled, homogenously dense, rimmed/laminated gallstones, respectively. The use of Hounsfield units did not show an advantage over gallstone pattern for predicting either response or final outcome to bile acid therapy. We conclude that computerized tomography analysis of gallstones is of value in predicting response to bile acid therapy and that gallstone pattern alone predicts response in most cases without the need for quantitative assessment.


Asunto(s)
Ácido Quenodesoxicólico/uso terapéutico , Colagogos y Coleréticos/uso terapéutico , Colelitiasis/diagnóstico por imagen , Colelitiasis/terapia , Tomografía Computarizada por Rayos X , Ácido Ursodesoxicólico/uso terapéutico , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Factores de Tiempo , Resultado del Tratamiento
20.
Clin Radiol ; 50(5): 335-7; discussion 337-8, 1995 May.
Artículo en Inglés | MEDLINE | ID: mdl-7743724

RESUMEN

Two cases are presented in which healing of oesophageal fistula was achieved by the radiologically-guided placement of tissue adhesive (enbucrilate, Histoacryl). With this relatively simple procedure, further surgical intervention under general anaesthesia was avoided.


Asunto(s)
Enbucrilato/administración & dosificación , Fístula Esofágica/terapia , Fístula/terapia , Enfermedades Pleurales/terapia , Radiología Intervencionista/métodos , Adulto , Fístula Esofágica/diagnóstico por imagen , Fístula/diagnóstico por imagen , Humanos , Masculino , Persona de Mediana Edad , Enfermedades Pleurales/diagnóstico por imagen , Radiografía
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