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1.
MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM.
Proc Natl Acad Sci U S A;
116(15): 7533-7542, 2019 04 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-30898885
2.
MM-141, an IGF-IR- and ErbB3-directed bispecific antibody, overcomes network adaptations that limit activity of IGF-IR inhibitors.
Mol Cancer Ther;
13(2): 410-25, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24282274
3.
Understanding the role of cross-arm binding efficiency in the activity of monoclonal and multispecific therapeutic antibodies.
Methods;
65(1): 95-104, 2014 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23872324
4.
Lessons learned from quantitative dynamical modeling in systems biology.
PLoS One;
8(9): e74335, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-24098642
5.
Impact of intrinsic affinity on functional binding and biological activity of EGFR antibodies.
Mol Cancer Ther;
11(7): 1467-76, 2012 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-22564724
6.
Antitumor activity of a novel bispecific antibody that targets the ErbB2/ErbB3 oncogenic unit and inhibits heregulin-induced activation of ErbB3.
Mol Cancer Ther;
11(3): 582-93, 2012 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-22248472
7.
Optimizing properties of antireceptor antibodies using kinetic computational models and experiments.
Methods Enzymol;
502: 67-87, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22208982
8.
Systems biologists seek fuller integration of systems biology approaches in new cancer research programs.
Cancer Res;
70(1): 12-3, 2010 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20028868
9.
Therapeutically targeting ErbB3: a key node in ligand-induced activation of the ErbB receptor-PI3K axis.
Sci Signal;
2(77): ra31, 2009 Jun 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-19567914
10.
Directional persistence of EGF-induced cell migration is associated with stabilization of lamellipodial protrusions.
Biophys J;
88(2): 1479-88, 2005 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-15713602
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