1.
Pediatr Blood Cancer
; 53(4): 658-60, 2009 Oct.
Artículo
en Inglés
| MEDLINE
| ID: mdl-19492322
RESUMEN
A 15-year-old male with congenital HIV infection was diagnosed with chronic myelogenous leukemia (CML) at age 4 years 9 months. HIV was initially treated with zidovudine. For the last >10 years he has received didanosine, lamivudine, and nelfinavir. CML was treated with Interferon alfa (INF-alpha) for >10 years and a brief course of hydroxyurea (HU). He remained in chronic phase CML since diagnosis however recent molecular monitoring revealed increased BCR/ABL transcripts necessitating a change in therapy to imatinib. The very prolonged chronic phase of CML in this patient has been unexpected especially in light of the underlying congenital HIV infection.
Asunto(s)
Infecciones por VIH/congénito , Infecciones por VIH/complicaciones , Leucemia Mieloide de Fase Crónica/tratamiento farmacológico , Adolescente , Humanos , Masculino , Factores de Tiempo
2.
Pediatr Infect Dis J
; 27(5): 480-1, 2008 May.
Artículo
en Inglés
| MEDLINE
| ID: mdl-18382381