1.
Chem Commun (Camb)
; 60(28): 3810-3813, 2024 Apr 02.
Artículo
en Inglés
| MEDLINE
| ID: mdl-38488056
RESUMEN
A novel probe C1 combining benzothiazole with a spiropyran section was developed for the specific detection of human serum albumin (HSA). The molecular docking suggested that the sulphonic acid group modification allowed C1 to form specific hydrogen bonds with lysine (Lys137) at fatty acid site 1 (FA1) of HSA, thus enabling fluorescence differentiation between HSA and BSA.
Asunto(s)
Albúmina Sérica Bovina , Albúmina Sérica Humana , Humanos , Albúmina Sérica Humana/química , Albúmina Sérica Bovina/química , Colorantes Fluorescentes/química , Simulación del Acoplamiento Molecular , Ácidos Grasos , Espectrometría de Fluorescencia , Unión Proteica
2.
Chem Commun (Camb)
; 56(57): 7925-7928, 2020 Jul 21.
Artículo
en Inglés
| MEDLINE
| ID: mdl-32529994
RESUMEN
In situ self-assembled boronate ester comprising commercially available 2-formylphenylboronic acid and 2-(2',3'-bihydroxyphenyl)benzothiazole (BHBT) is explored for the detection of ONOO- with product-boosted fluorescence. The self-assembly can detect ONOO- in the endoplasmic reticulum of living cells.