Detalles de la búsqueda
1.
Applied physiologically-based pharmacokinetic modeling to assess uridine diphosphate-glucuronosyltransferase-mediated drug-drug interactions for Vericiguat.
CPT Pharmacometrics Syst Pharmacol;
13(1): 79-92, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-37794724
2.
Physiologically based pharmacokinetic (PBPK) modelling of oral drug absorption in older adults - an AGePOP review.
Eur J Pharm Sci;
188: 106496, 2023 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37329924
3.
Classification of Breast Cancer Histopathological Images Using DenseNet and Transfer Learning.
Comput Intell Neurosci;
2022: 8904768, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36262621
4.
Nifurtimox for Treatment of Chagas Disease in Pediatric Patients: the Challenges of Applying Pharmacokinetic-Pharmacodynamic Principles to Dose Finding.
AAPS J;
24(5): 92, 2022 08 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-36002604
5.
Model-informed bridging of rivaroxaban doses for thromboprophylaxis in pediatric patients aged 9 years and older with congenital heart disease.
CPT Pharmacometrics Syst Pharmacol;
11(8): 1111-1121, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35665486
6.
Population Pharmacokinetics of Nifurtimox in Adult and Pediatric Patients With Chagas Disease.
J Clin Pharmacol;
62(10): 1273-1284, 2022 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35460577
7.
Population pharmacokinetic analysis of rivaroxaban in children and comparison to prospective physiologically-based pharmacokinetic predictions.
CPT Pharmacometrics Syst Pharmacol;
10(10): 1195-1207, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34292671
8.
Clinical investigation of the biopharmaceutical characteristics of nifurtimox tablets - Implications for quality control and application.
Eur J Pharm Sci;
166: 105940, 2021 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34265407
9.
Predictive Performance of Physiology-Based Pharmacokinetic Dose Estimates for Pediatric Trials: Evaluation With 10 Bayer Small-Molecule Compounds in Children.
J Clin Pharmacol;
61 Suppl 1: S70-S82, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-34185905
10.
A generic framework for the physiologically-based pharmacokinetic platform qualification of PK-Sim and its application to predicting cytochrome P450 3A4-mediated drug-drug interactions.
CPT Pharmacometrics Syst Pharmacol;
10(6): 633-644, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33946131
11.
Integration of physiological changes during the postpartum period into a PBPK framework and prediction of amoxicillin disposition before and shortly after delivery.
J Pharmacokinet Pharmacodyn;
47(4): 341-359, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32748112
12.
Predictive Pediatric Modeling and Simulation Using Ontogeny Information.
J Clin Pharmacol;
59 Suppl 1: S95-S103, 2019 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31502689
13.
Applied Concepts in PBPK Modeling: How to Extend an Open Systems Pharmacology Model to the Special Population of Pregnant Women.
CPT Pharmacometrics Syst Pharmacol;
7(7): 419-431, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29569837
14.
A Physiologically Based Pharmacokinetic Model for Pregnant Women to Predict the Pharmacokinetics of Drugs Metabolized Via Several Enzymatic Pathways.
Clin Pharmacokinet;
57(6): 749-768, 2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-28924743
15.
Physiologically Based Pharmacokinetic Modeling of Renally Cleared Drugs in Pregnant Women.
Clin Pharmacokinet;
56(12): 1525-1541, 2017 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-28391404
16.
Gestation-Specific Changes in the Anatomy and Physiology of Healthy Pregnant Women: An Extended Repository of Model Parameters for Physiologically Based Pharmacokinetic Modeling in Pregnancy.
Clin Pharmacokinet;
56(11): 1303-1330, 2017 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-28401479
17.
Developing a mobile application to better inform patients and enable effective consultation in implant dentistry.
Comput Struct Biotechnol J;
14: 252-61, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27453770
18.
Evaluation of changes in oral drug absorption in preterm and term neonates for Biopharmaceutics Classification System (BCS) class I and II compounds.
Br J Clin Pharmacol;
81(1): 137-47, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26302359
19.
Developmental changes in the expression and function of cytochrome P450 3A isoforms: evidence from in vitro and in vivo investigations.
Clin Pharmacokinet;
52(5): 333-45, 2013 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-23463352
20.
A novel maturation function for clearance of the cytochrome P450 3A substrate midazolam from preterm neonates to adults.
Clin Pharmacokinet;
52(7): 555-65, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23512668