Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 104
Filtrar
Más filtros

Base de datos
País/Región como asunto
Tipo del documento
Intervalo de año de publicación
1.
Int J Exerc Sci ; 17(1): 1056-1067, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-39257648

RESUMEN

Extreme postures and imbalances in neuromuscular activity may place classical ballet dancers at higher risk of injury. Dance studio mirrors provide visual feedback by which a dancer can self-correct their body position and alignment, but have been suggested to negatively impact kinesthetic abilities and decrease performance capabilities. Thus, we investigated the effects of a mirror on muscle activity of the quadriceps, heart rate (HR), rating of perceived exertion (RPE), and qualitative performance. A lack of visual feedback would increase muscle activity of the quadriceps, HR, and RPE, and decrease self-reported perception of technical quality. 10 female participants completed a single leg balance, an adagio, and a jump task twice - once in each condition. Muscle activity of the vastus lateralis (VL) and vastus medialis oblique (VMO), as well as HR and RPE were assessed during each combination. Qualitative performance was assessed with an exit survey. No significant differences were found between conditions for RPE or HR in all three tasks (RPE: Balance p = 0.468, Adagio p = 0.191, Jumps p = 0.769; HR: Balance p = 0.409, Adagio p = 0.424, Jumps p = 0.244). No significant differences were found between conditions/tasks for peak, mean, and RMS sEMG. Dancers significantly ranked their artistic expression lower in a non-mirror condition (p = 0.018, Cohen's d = 0.775). No differences in muscle activity of the VMO and VL or vital signs of fatigue were found. Psychological implications of visual feedback, including dancer's perceived decrease in artistic expression without a mirror present, should be further explored in future studies.

3.
Nutrients ; 16(16)2024 Aug 06.
Artículo en Inglés | MEDLINE | ID: mdl-39203726

RESUMEN

Parenteral nutrition (PN) is a life-sustaining method to provide adequate nutrients to patients unable to receive oral or enteral nutrition. PN typically contains a mixture of macro- and micro-nutrients, although the lipid composition has been identified as a concern for liver disease. Therefore, the study of the intravenous lipid emulsion (ILE) prescribing practices in home-based PN (HPN) patients and whether differing lipid PN alters liver function tests (LFTs) is needed. METHODS: A retrospective study of monthly LFTs from a random sample of 105 adult HPN patients in the U.S. over a 6-month period was conducted. Patients were receiving olive oil/soy oil (n = 53, Clinolipid), mixed ILE (n = 39, SMOF Lipid), soy oil (SO; n = 4, Intralipid), or none (n = 7). LFTs monitored were alkaline phosphatase (ALP), alanine transaminase (ALT), aspartate transaminase (AST), and total bilirubin (T Bili). RESULTS: No differences were observed in baseline LFTs across groups (all, p > 0.25, η2 < 0.04), nor were there differences in age, body mass index, days of PN, or mean PN volume (all, p > 0.36, η2 < 0.05). There were no significant interactions between ILE type and time (all p > 0.64, ηp2 < 0.03), no effect of ILE type (all p > 0.60, ηp2 < 0.03), and no effect of time (all p > 0.69, ηp2 < 0.01) in terms of LFTs. Average LFTs over six months were also not different between ILE types (all p > 0.30, η2 < 0.04). CONCLUSION: These findings suggested that patients were mostly prescribed mixed or ILE PN containing more than one lipid source and that differing ILEs in long-term HPN patients did not alter LFTs over a six-month period.


Asunto(s)
Emulsiones Grasas Intravenosas , Pruebas de Función Hepática , Hígado , Aceite de Oliva , Aceite de Soja , Humanos , Estudios Retrospectivos , Emulsiones Grasas Intravenosas/administración & dosificación , Masculino , Femenino , Aceite de Soja/administración & dosificación , Persona de Mediana Edad , Aceite de Oliva/administración & dosificación , Anciano , Hígado/metabolismo , Adulto , Nutrición Parenteral , Bilirrubina/sangre , Fosfolípidos/administración & dosificación , Alanina Transaminasa/sangre , Aspartato Aminotransferasas/sangre , Nutrición Parenteral en el Domicilio , Pautas de la Práctica en Medicina/estadística & datos numéricos , Emulsiones/administración & dosificación , Fosfatasa Alcalina/sangre , Hepatopatías , Aceites de Pescado , Triglicéridos
4.
Physiol Rep ; 12(12): e16120, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-39031617

RESUMEN

Wildfire smoke (WFS) is an urgent and rapidly growing threat to global health. Aside from obvious threats to pulmonary function, increases in cardiac abnormalities or myocardial infarction have been documented during WF season, but little is known about the effects of WFS on cardiovascular health. We investigated the effect of nonoccupational WFS exposure on cardiovascular and pulmonary function at rest and during graded handgrip exercise through a case series of young, healthy adults (n = 4, 25 ± 6 years) assessed after ≥3 days of bad or good air quality. Peripheral and estimated central blood pressures, vascular stiffness, and microvascular function (Near infrared spectroscopy, NIRS) were assessed at rest, and during rhythmic handgrip exercise. WFS did not appear to alter resting peripheral, central BP, or vascular stiffness (all, p > 0.05). Slope 1 and slope 2 from the NIRS-vascular occlusion test (NIRS-VOT) were not different between conditions (p > 0.05). The change in SmO2 during exercise was lower (p = 0.02, η p 2 $$ {\eta}_{\mathrm{p}}^2 $$ = 0.62) with bad air quality. These preliminary findings suggest modest effects of environmental WFS exposure on muscle microvascular function during exercise in healthy adults. Future work is needed to elucidate the physiological changes with WFS exposure and the increased risk of cardiovascular events, perhaps exacerbated through physical activity.


Asunto(s)
Ejercicio Físico , Fuerza de la Mano , Humo , Incendios Forestales , Humanos , Fuerza de la Mano/fisiología , Adulto , Masculino , Humo/efectos adversos , Femenino , Ejercicio Físico/fisiología , Exposición a Riesgos Ambientales/efectos adversos , Microcirculación/fisiología , Microcirculación/efectos de los fármacos , Adulto Joven , Consumo de Oxígeno/fisiología , Rigidez Vascular , Espectroscopía Infrarroja Corta , Presión Sanguínea
5.
Eur J Appl Physiol ; 124(10): 3105-3115, 2024 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-38819659

RESUMEN

PURPOSE: The involvement of central command in central hemodynamic regulation during exercise is relatively well-known, although its contribution to peripheral hemodynamics at the onset of low-intensity contractions is debated. This study sought to examine central and peripheral hemodynamics during electrically-evoked muscle contractions (without central command) and voluntary muscle activity (with central command). METHODS: Cyclic quadriceps isometric contractions (1 every second), either electrically-evoked (ES; 200 ms trains composed of 20 square waves) or performed voluntarily (VC), were executed by 10 healthy males (26 ± 3 years). In both trials, matched for force output, peripheral and central hemodynamics were analysed. RESULTS: At exercise onset, both ES and VC exhibited equal peaks of femoral blood flow (1276 ± 849 vs. 1117 ± 632 ml/min, p > 0.05) and vascular conductance (15 ± 11 vs. 13 ± 7 ml/min/mmHg, p > 0.05), respectively. Similar peaks of heart rate (86 ± 16 bpm vs. 85 ± 16 bpm), stroke volume (100 ± 20 vs. 99 ± 27 ml), cardiac output (8.2 ± 2.5 vs. 8.5 ± 2.1 L/min), and mean arterial pressure (113 ± 13 vs. 113 ± 3 mmHg), were recorded (all, p > 0.05). After ~ 50 s, all the variables drifted to lower values. Collectively, the hemodynamics showed equal responses. CONCLUSION: These results suggest a similar pathway for the initial (first 40 s) increase in central and peripheral hemodynamics. The parallel responses may suggest an initial minimal central command involvement during the onset of low-intensity contractions, likely associated with a neural drive activation delay or threshold.


Asunto(s)
Ejercicio Físico , Hemodinámica , Contracción Isométrica , Humanos , Masculino , Adulto , Hemodinámica/fisiología , Ejercicio Físico/fisiología , Contracción Isométrica/fisiología , Frecuencia Cardíaca/fisiología , Músculo Cuádriceps/fisiología , Músculo Cuádriceps/irrigación sanguínea , Músculo Esquelético/fisiología , Gasto Cardíaco/fisiología
6.
Dis Aquat Organ ; 157: 95-106, 2024 Mar 14.
Artículo en Inglés | MEDLINE | ID: mdl-38546193

RESUMEN

Parasitic sea lice (Copepoda: Caligidae) colonising marine salmonid (Salmoniformes: Salmonidae) aquaculture production facilities have been implicated as a possible pressure on wild salmon and sea trout populations. This investigation uses monitoring data from the mainland west coast and Western Isles of Scotland to estimate the association of the abundance of adult female Lepeophtheirus salmonis (Krøyer) colonising farmed Atlantic salmon Salmo salar L. with the occurrence of juvenile and mobile L. salmonis on wild sea trout, anadromous S. trutta L. The associations were evaluated using generalised linear mixed models incorporating farmed adult female salmon louse abundances which are temporally lagged relative to dependent wild trout values. The pattern of lags, which is consistent with time for L. salmonis development between egg and infective stage, was evaluated using model deviances. A significant positive association is identified between adult female L. salmonis abundance on farms and juvenile L. salmonis on wild trout. This association is consistent with a causal relationship in which increases in the number of L. salmonis copepodids originating from lice colonising farmed Atlantic salmon cause an increase of L. salmonis abundance on wild sea trout.


Asunto(s)
Copépodos , Enfermedades de los Peces , Salmo salar , Animales , Femenino , Trucha , Acuicultura , Escocia/epidemiología , Enfermedades de los Peces/epidemiología , Enfermedades de los Peces/parasitología
7.
Physiol Rep ; 12(6): e15988, 2024 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-38537943

RESUMEN

The downward slope during the near-infrared spectroscopy (NIRS)-vascular occlusion test (NIRS-VOT) is purported as a simplified estimate of metabolism. Whether or not the NIRS-VOT exhibits sex- or limb-specificity or may be acutely altered remains to be elucidated. Thus, we investigated if there is limb- or sex specificity in tissue desaturation rates (DeO2) during a NIRS-VOT, and if acute dietary capsaicin may alter this estimate of muscle metabolism. Young healthy men (n = 25, 21 ± 4 years) and women (n = 20, 20 ± 1 years) ingested either placebo or capsaicin, in a counterbalanced, single-blind, crossover design after which a simplified NIRS-VOT was conducted to determine the DeO2 (%/s), as an estimate of oxidative muscle metabolism, in both the forearm (flexors) and thigh (vastus lateralis). There was a significant limb effect with the quadriceps having a greater DeO2 than the forearm (-2.31 ± 1.34 vs. -1.78 ± 1.22%/s, p = 0.007, ηp 2 = 0.19). There was a significant effect of sex on DeO2 (p = 0.005, ηp 2 = 0.203) with men exhibiting a lesser DeO2 than women (-1.73 ± 1.03 vs. -2.36 ± 1.32%/s, respectively). This manifested in significant interactions of limb*capsaicin (p = 0.001, ηp 2 = 0.26) as well as limb*capsaicin*sex on DeO2 (p = 0.013, ηp 2 = 0.16) being observed. Capsaicin does not clearly alter O2-dependent muscle metabolism, but there was apparent limb and sex specificity, interacting with capsaicin in this NIRS-derived assessment.


Asunto(s)
Capsaicina , Enfermedades Vasculares , Femenino , Humanos , Masculino , Capsaicina/farmacología , Músculo Esquelético/metabolismo , Consumo de Oxígeno/fisiología , Método Simple Ciego , Espectroscopía Infrarroja Corta/métodos , Enfermedades Vasculares/metabolismo
8.
Complement Ther Med ; 80: 103022, 2024 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-38191033

RESUMEN

Watching news broadcasts is known to elicit psychological stress. Conversely, the iconic painter Bob Ross (BR) has risen to pop culture status and amassed a following, as many find the messages and sounds of BR to be soothing and relaxing. Though, it has yet to be directly tested if such exposure can confer psychological or physiological benefit. The purpose of this study was to compare the effects of watching BR versus streaming news on markers of cardiovascular health and profile of mood states (POMS). It was hypothesized that watching BR would increase POMS scores and heart rate variability (HRV). It was also hypothesized that watching the news would increase blood pressure (BP), vascular stiffness (VS), and heart rate (HR). METHODS: In a randomized, controlled, crossover design, 18 young (21 ± 1 yrs, 9 female, 9 male) healthy participants (172.6 ± 9.9 cm, 69 ± 18 kg) were assessed for BP, VS, HR, HRV, and POMS before and after watching an episode of BR or the News matched for time (∼27 mins). RESULTS: A significant interaction effect on POMS scores were observed for, anxiety (p = 0.01), anger (p = 0.008), depression (p = 0.003), fatigue (p = 0.001), and confusion (p = 0.01) domains after watching BR. The LF/HF ratio, an HRV marker of sympathovagal balance, was significantly lower after watching BR (p = 0.04). There were no significant time, condition, or interaction effects on systolic BP, mean arterial pressure, and diastolic BP. CONCLUSION: The "Bob Ross Effect" reduces overall mood disturbance, though appears to exert little influence on the cardiovascular system in this acute paradigm.


Asunto(s)
Ansiedad , Corazón , Femenino , Humanos , Masculino , Presión Sanguínea , Frecuencia Cardíaca/fisiología , Estrés Psicológico , Estudios Cruzados , Adulto Joven
9.
Artículo en Inglés | MEDLINE | ID: mdl-38131715

RESUMEN

The public-health restrictions (e.g., remote learning, restricted access to facilities and dining halls) put in place by colleges to reduce the spread of COVID-19 resulted in forced isolation and modifications to health-related behaviors. The restrictions and uncertainty associated with COVID-19 may have exacerbated the challenges of meeting exercise recommendations and mental-health concerns. The purpose of this study was to assess the impact of restrictions on students' exercise habits and their levels of anxiety, stress, and depression. Five-hundred and forty students completed a 29-question survey on individual demographics, living arrangements, exercise, sleep, diet, and mental health. Significant changes in weekly days of exercise and intensity were reported. Increases in anxiety, stress, and depression were reported. The two most frequently reported changes in exercise behavior were an increase in minutes of aerobic training (5%) and a combination of reduced minutes of aerobic and resistance training (3.9%), which could be reflective of an individual's ability and/or desire to maintain exercise behavior during the restrictions. Alternatively, for those students who reduced their exercise habits, aerobic training (11%) was the mode that suffered the most. Demographic factors such as ethnicity, regional residence, and gender were found to have significant effects on stress, anxiety, and depression. Amidst pandemics and future health emergencies, colleges should prioritize establishing opportunities for students to exercise, helping them meet physical activity recommendations and combat mental-health issues.


Asunto(s)
COVID-19 , Humanos , COVID-19/epidemiología , Salud Mental , Autoinforme , SARS-CoV-2 , Ansiedad/epidemiología , Ansiedad/psicología , Ejercicio Físico/psicología , Estudiantes/psicología , Depresión/epidemiología , Depresión/psicología
10.
Artículo en Inglés | MEDLINE | ID: mdl-37998306

RESUMEN

Despite great strides in the development of contraceptive technologies, the United States has one of the highest teen pregnancy rates in the world. Religion and associated values may shape the sexual health behaviors of college students, as prior studies have aimed to determine how social factors may influence the use of contraception amongst college students. Thus, we sought to examine the differences in current contraceptive methods and the age of first contraceptive usage among sexually active female college students with different religious affiliations and strengths of religiosity. It was hypothesized that there would be no difference in current contraceptive methods among different religious affiliations and strengths of religions and that there would be a difference in the age of first contraceptive usage among different religious affiliations and strengths of religiosity. Two hundred and twenty-four college-aged females completed a 20-question survey about sexual health and religious practices. Chi-squared tests were implemented to determine the frequencies of responses across religious affiliations and strengths of religiosity. Significant differences in the frequency of responses for the age of first contraceptive usage were observed across different strengths of religiosity (p = 0.016) and for the self-perceived impact of religion on sexual health across different religious affiliations (p = 0.033) and strengths of religiosity (p = 0.005). All other differences were found not to be statistically significant. It was determined that increased strengths of religiosity resulted in delayed onset of contraceptive usage and that both different religious affiliations and greater strengths of religiosity lead to different self-perceived impacts of religion on sexual health despite low levels of current practice.


Asunto(s)
Salud Sexual , Embarazo , Adolescente , Humanos , Femenino , Estados Unidos , Adulto Joven , Religión , Conducta Sexual , Anticoncepción , Estudiantes
11.
Physiol Rep ; 11(22): e15856, 2023 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-37985125

RESUMEN

Overweight and obesity (Ow/Ob) is a risk factor for cardiometabolic disease. Caloric restriction (CR) have been investigated but little is known about the acute effects of CR and often such diets are not standardized. Thus, we aimed to assess the impact of a new standardized 3-day CR diet (590 kcal/d intake) on cardiometabolic health in weight-stable Ow/Ob individuals. In a single-arm design, 15 Ow/Ob men and women were assessed pre-post a 3-day standardized CR diet; specifically, body weight/composition (%body fat, visceral fat score (Vfs), blood pressure (BP), and vascular stiffness (VS), resting energy expenditure (REE), substrate utilization (respiratory quotient, RQ), and blood glucose/lipid profile). CR lowered body weight (93.1 ± 15.2 to 90.67 ± 14.4 kg, p < 0.001, d = 1.9), %fat (37.2 ± 7.5 to 35.8 ± 7.5%, p = 0.002, d = 1.1), and Vfs (13.1 ± 4.5 to 12.2 ± 3.9 a.u., p = 0.002, d = 1.1), but not body water (46.3 ± 3.6 to 46.0 ± 3.6%, p = 0.29). CR lowered VS (29.8 ± 17.5 to 21.5 ± 14.5%, p = 0.05, d = 0.6), but not BP (p > 0.05). Blood glucose (86 ± 7 to 84 ± 11 mg/dL, p = 0.33) and lipids (total cholesterol (196 ± 49 to 203 ± 54 mg/dL, p = 0.16) and TC/HDL (4.9 ± 2.4 to 6.1 ± 4.7, p = 0.13)) were unchanged. RQ decreased with CR (0.84 ± 0.01 to 0.76 ± 0.00, p < 0.001, d = 1.9), though REE was unchanged (p = 0.83). The 3-day CR diet significantly improved fat metabolism, body weight and composition, and vascular stiffness.


Asunto(s)
Enfermedades Cardiovasculares , Sobrepeso , Femenino , Humanos , Masculino , Glucemia/metabolismo , Restricción Calórica , Enfermedades Cardiovasculares/etiología , Enfermedades Cardiovasculares/prevención & control , Obesidad/metabolismo , Sobrepeso/metabolismo , Pérdida de Peso
12.
Front Sports Act Living ; 5: 1245788, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37691642

RESUMEN

Elite athletes require a delicate balance of physiological and psychological stress and recovery-essential for achieving optimal performance. Monitoring heart rate variability (HRV) provides a non-invasive estimation of both physiological and psychological stress levels, offering potentially valuable insights into health, performance, and adaptability. Previous studies, primarily conducted on male participants, have shown an association between HRV and performance in the context of rowing training. However, given the rigorous nature of rowing training, it is crucial to investigate HRV in elite rowers, particularly during the U.S. national selection regattas (NSR). Purpose: To comprehensively analyze elite female rowers, evaluating acute changes in HRV and subjective psychometrics during the NSR. Methods: Five elite female rowers (26 ± 2 years, 180 ± 8 cm, 82 ± 8 kg, 19 ± 6%fat) were recruited and tracked prior to and during NSR I and II. Morning HRV measures were completed using photoplethysmography (HRV4training) along with self-reported levels of fatigue, soreness, rating of perceived exertion, mentally energy and physical condition. Results: Significant decreases were observed in log transformed root-mean square of successive differences (LnRMSSD; p = 0.0014) and fatigue (p = 0.01) from pre-to-during NSR, while mental energy (p = 0.01), physical condition (p = 0.01), and motivation (p = 0.006) significantly increased. These psychometric measures returned to pre-NSR levels, at post-NSR (all p < 0.05), though HRV remained slightly suppressed. NSR on-water performance was not correlated to LnRMSSD or the change in LnRMSSD (p > 0.05). Discussion: HRV and psychometric measures are sensitive to the stress of elite rowing competition in females. However, HRV was not associated with on-water rowing performance during an elite rowing competition.

13.
BMC Sports Sci Med Rehabil ; 15(1): 83, 2023 Jul 11.
Artículo en Inglés | MEDLINE | ID: mdl-37434243

RESUMEN

BACKGROUND: Heat stress during aerobic exercise training may offer an additional stimulus to improve cardiovascular function and performance in a cool-temperate environment. However, there is a paucity of information on the additive effects of high-intensity interval exercise (HIIE) and acute heat stress. We aimed to determine the effects of HIIE in combination with acute heat stress on cardiovascular function and exercise performance. METHODS: Twelve active (peak O2 consumption [VO2peak]: 47 ± 8 ml·O2/min/kg) young adults were counterbalanced to six sessions of HIIE in hot (HIIE-H, 30 ± 1 °C, 50 ± 5% relative humidity [RH]) or temperate conditions (HIIE-T, 20 ± 2 °C, 15 ± 10% RH). Resting heart rate (HR), HR variability (HRV), central (cBP) and peripheral blood pressure (pBP), peripheral mean arterial pressure (pMAP), pulse wave velocity (PWV), VO2peak, and 5-km treadmill time-trial were measured pre- and post-training. RESULTS: Resting HR and HRV were not significantly different between groups. However, expressed as percent change from baseline, cSBP (HIIE-T: + 0.9 ± 3.6 and HIIE-H: -6.6 ± 3.0%, p = 0.03) and pSBP (HIIE-T: -2.0 ± 4.6 and HIIE-H: -8.4 ± 4.7%, p = 0.04) were lower in the heat group. Post-training PWV was also significantly lower in the heat group (HIIE-T: + 0.4% and HIIE-H: -6.3%, p = 0.03). Time-trial performance improved with training when data from both groups were pooled, and estimated VO2peak was not significantly different between groups (HIIE-T: 0.7% and HIIE-H: 6.0%, p = 0.10, Cohen's d = 1.4). CONCLUSIONS: The addition of acute heat stress to HIIE elicited additive adaptations in only cardiovascular function compared to HIIE alone in active young adults in temperate conditions, thus providing evidence for its effectiveness as a strategy to amplify exercise-induced cardiovascular adaptations.

15.
Prev Vet Med ; 214: 105888, 2023 May.
Artículo en Inglés | MEDLINE | ID: mdl-36906938

RESUMEN

For effective wild salmon (Salmo salar) conservation in areas where aquaculture of salmon is practiced it is necessary to identify where the key parasite, the salmon louse (Lepeophtheirus salmonis), will have an impact on these wild salmon. A simple modelling structure is implemented in a sample system in Scotland for assessing interaction between wild salmon and salmon lice from salmon farms. The model is demonstrated for case studies of smolt sizes and migration routes through salmon lice concentration fields derived for average farm loads from 2018 to 2020. Lice modelling describes production and distribution of lice, infection rates on hosts and biological development of lice. The modelling framework allows explicit assessment of the relationships between lice production, lice concentration and impact on hosts as they grow and migrate. Lice distribution in the environment is determined using a kernel model, which summarises mixing in a complex hydrodynamic system. Smolt modelling describes their initial size, growth and migration pathways. This is illustrated for a set of parameter values applied to 10 cm, 12.5 cm and 15 cm salmon smolts. We found that salmon lice impact depends on initial size of host, smaller smolts will be more susceptible, while larger smolts are less impacted by a given number of lice encounters and migrate more rapidly. This modelling framework can be adapted to allow evaluation of threshold concentrations of lice in the water that should not be exceeded to avoid impacts on smolt populations.


Asunto(s)
Copépodos , Enfermedades de los Peces , Parásitos , Salmo salar , Animales , Enfermedades de los Peces/parasitología , Acuicultura
16.
Eur J Appl Physiol ; 123(5): 1041-1050, 2023 May.
Artículo en Inglés | MEDLINE | ID: mdl-36633663

RESUMEN

PURPOSE: Heart rate variability (HRV) estimates the autonomic nervous system (ANS) influence on the heart and appears sex-specific. Sensory afferents exhibit sex-specificity; although, it is unknown if Capsaicin, an agonist for transient receptor potential vanilloid channel-1 (TRPV1), alters cardiac ANS activity in a sex-dependent manner, which could be important given the predictive nature of HRV on risk of developing hypertension. Thus, we explored if there was sex-specificity in the effect of capsaicin on estimated cardiac ANS activity. METHODS: HRV was measured in 38 young males (M: n = 25) and females (F: n = 13), in a blinded-crossover design, after acute ingestion of placebo or capsaicin. Resting HR, RR-interval, root-mean-square of successive differences (RMSSD), natural log-transformed RMSSD (LnRMSSD), standard deviation of n-n intervals (SDNN), number of pairs of successive n-n intervals differing by > 50 ms (NN50), and percent NN50 (PNN50) were obtained using standard techniques. RESULTS: Significant sex differences were observed in mean HR (M: 59 ± 9.3 vs. F: 65 ± 12 beats/min, p = 0.036, η2 = 0.098), minimum HR (M: 47 ± 8.3 vs. F: 56 ± 12 beats/min, p = 0.014, η2 = 0.124), and NN50 (M: 177 ± 143 vs. F: 29 ± 17, p < 0.001, η2 = 0.249). There was a significant interaction of sex*treatment (p = 0.02, η2 = 0.027) for RMSSD, where males increased (78 ± 55 vs. 91 ± 64 ms), and females decreased (105 ± 83 vs. 76 ± 43 ms), placebo vs. capsaicin. CONCLUSION: This controlled study recapitulates sex differences in HR and HRV, but revealed a sexual dimorphism in the parasympathetic response to capsaicin, perhaps due to differing TRPV1-afferent sensitivity, highlighting a potential mechanism for differential regulation of hemodynamics, and CVD risk, and should be considered in future studies.


Asunto(s)
Capsaicina , Caracteres Sexuales , Humanos , Masculino , Femenino , Frecuencia Cardíaca/fisiología , Capsaicina/farmacología , Sistema Nervioso Autónomo/fisiología , Corazón
17.
Microvasc Res ; 145: 104436, 2023 01.
Artículo en Inglés | MEDLINE | ID: mdl-36113667

RESUMEN

Endothelial dysfunction is associated with cardiovascular disease development, nitric oxide (NO) deficiencies, and may be limb or sex-specific. Prior in vitro work indicated that the transient receptor potential vanilloid channel-1 (TRPV1) is expressed in human arteries and the TRPV1 agonist capsaicin alters vasodilation in an endothelium-dependent manner; however, it is unknown if this translates in vivo or is limb or sex-dependent. Therefore, we sought to determine if there was limb or sex-specificity in the effect of capsaicin on microvascular function using near-infrared spectroscopy (NIRS)-derived tissue oxygen saturation (StO2) reperfusion slope. In a blinded placebo-controlled crossover design, 45 young males (M: n = 25) and females (F: n = 20), the reperfusion slopes of the forearm and quadriceps were assessed, and a urine sample obtained to assay for nitrate/nitrite (NOx) concentrations and antioxidant capacity after acutely ingesting placebo or capsaicin. Under placebo, females had greater reperfusion rates in both the forearm (M: 0.44 ± 0.24 vs. F: 0.98 ± 0.46 %/sec; p = 0.002, d = -1.50) and quadricep (M: 0.86 ± 0.31 vs. F: 1.17 ± 0.43 %/sec; p = 0.010, d = -0.85). Capsaicin decreased microvascular responsiveness in the forearm of females (placebo: 0.98 ± 0.45 vs. capsaicin: 0.84 ± 0.45 %/sec) as compared to males (placebo: 0.45 ± 0.24 vs. capsaicin: 0.38 ± 0.16 %/sec, interaction p < 0.001, η2 = 0.475). There was a sex*treatment interaction for NOx concentrations, where males increased (placebo: 21.13 ± 12.83 vs. capsaicin: 23.82 ± 13.34 µM), while females decreased (placebo: 22.78 ± 14.40 vs. capsaicin: 14.43 ± 10.01 µM; p = 0.037, η2 = 0.042). Using NIRS to assess microvascular function, there is apparent limb and sex-specificity, and, for the first-time, document that acute oral capsaicin alters reperfusion slope in a sexually divergent manner.


Asunto(s)
Capsaicina , Espectroscopía Infrarroja Corta , Masculino , Femenino , Humanos , Capsaicina/farmacología , Músculo Esquelético/irrigación sanguínea , Vasodilatación , Antebrazo
18.
Obesity (Silver Spring) ; 31 Suppl 1: 139-149, 2023 02.
Artículo en Inglés | MEDLINE | ID: mdl-36575144

RESUMEN

OBJECTIVE: This study compared intermittent fasting and protein pacing (IF-P) versus a heart-healthy caloric restriction (CR) diet, matched for energy intake and physical activity energy expenditure, on body weight, total and visceral fat mass, and cardiometabolic health outcomes in adults with obesity. METHODS: IF-P (n = 21) and CR (n = 20) were assessed pre- (week 0), mid- (week 5), and post- (week 9) intervention. RESULTS: Both groups reduced (p < 0.05) weight, total and visceral fat mass, blood pressure and lipids, and desire to eat food and increased proportion of fat-free mass. IF-P resulted in greater (p < 0.05) reductions in weight (-9% vs. -5%), total (-16% vs. -9%) and visceral (-33% vs. -14%) fat mass, and desire to eat (-17% vs. 1%) and increased fat-free mass percent (6% vs. 3%) compared with CR. These improvements were despite similar weekly total energy intake (IF-P, 9470 ± 550 vs. CR, 9095 ± 608 kcal/wk; p = 0.90) and physical activity energy expenditure (IF-P, 300 ± 150 vs. CR, 350 ± 200 kcal/d; p = 0.79). CONCLUSIONS: IF-P and CR optimize weight loss, body composition, cardiometabolic health, and hunger management, with IF-P providing greater benefits.


Asunto(s)
Restricción Calórica , Enfermedades Cardiovasculares , Adulto , Humanos , Restricción Calórica/métodos , Dieta Reductora/métodos , Grasa Intraabdominal , Ayuno Intermitente , Composición Corporal , Ayuno
19.
Int J Exerc Sci ; 16(6): 1244-1256, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-38288384

RESUMEN

Blood flow restriction training (BFRT) uses occlusion during low-intensity resistance training (< 50% of 1-repetition maximum, 1RM) to reduce arterial blood flow and venous return, imposing greater metabolic stress but similar muscular hypertrophy and strength gains as high-intensity resistance training (HIRT). However, no study, to date, has incorporated BFRT in a collegiate strength and conditioning setting to assess ecological validity. We aimed to investigate the effects of adding 6-weeks of accessory BFRT or HIRT to NCAA Division III soccer players prescribed resistance training regimen on muscle strength and size. Male and female (n = 17) athletes were randomly assigned to complete biceps curls 2x/week under BFRT or control (HIRT), following regularly scheduled strength training. Bicep strength (1RM) and circumference (BC) were assessed at weeks 0, 3, and 6 (men only). In men, for BC no significant interaction of condition x time was observed (p = 0.861), though condition (BFRT vs Control, p = 0.025) and time (p = 0.024) were significant. For 1RM, there was no significant interaction of condition x time (BFRT vs HIRT, p = 0.067) or of condition (p = 0.598), but there was a significant effect of time (p = 0.004). In women, there was no significant interaction between time and condition (p = 0.765) or of condition (p = 0.971) on BC, but time was significant (p = 0.045). For 1RM, there was no significant interaction of condition x time (p = 0.227) or of condition (p = 0.741), but time was (p = 0.018). In this preliminary ecological study, BFRT induced similar increases in muscle strength and circumference as HIRT in soccer players, suggesting that BFRT could be incorporated into collegiate athlete training.

20.
Int J Exerc Sci ; 16(6): 1320-1333, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-38288383

RESUMEN

The American College of Sports Medicine recommends resistance training using at least 70% one repetition maximum to improve muscular strength and hypertrophy; however, these intensities may not be safe for all populations. A training technique that has been reported to elicit increases in strength and muscle size uses low intensity resistance training or low load training in combination with blood flow restriction (BFR) to the working muscle. Although the acute effects of BFR on muscle strength and size are well established, the effects of BFR on muscular power are not definitively known. Resistance trained males (n = 14) completed three experimental sessions in which lower body power output and vertical jump height were measured pre and post exercise protocol. The barbell back squat was performed with either low load and blood flow restriction, high load (90% 1 RM, HL), or control (CON). A significant mean difference between pre (M = 46.35 ± 5.61 cm) and post (M = 43.63 ± 4.59 cm) vertical jump heights following 15 repetitions at 20% 1 RM with BFR was observed (p = 0.034), but not with HL or a CON. A decrement in vertical jump height was experienced after an acute bout of BFR with low load resistance exercise. Low load resistance exercise with BFR or high intensity resistance exercise may not be beneficial as part of a warm-up to acutely enhance vertical jump or power output.

SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA