Búsqueda | Portal Regional de la BVS Paraguay

1.

Orexin Receptor Antagonism: Normalizing Sleep Architecture in Old Age and Disease.

Kron, Jarrah O-Z J; Keenan, Ryan J; Hoyer, Daniel; Jacobson, Laura H.

Annu Rev Pharmacol Toxicol; 64: 359-386, 2024 Jan 23.

Artículo en Inglés | MEDLINE | ID: mdl-37708433

2.

Orexin 2 receptor antagonism sex-dependently improves sleep/wakefulness and cognitive performance in tau transgenic mice.

Keenan, Ryan J; Daykin, Heather; Metha, Jeremy; Cornthwaite-Duncan, Linda; Wright, David K; Clarke, Kyra; Oberrauch, Sara; Brian, Maddison; Stephenson, Sarah; Nowell, Cameron J; Allocca, Giancarlo; Barnham, Kevin J; Hoyer, Daniel; Jacobson, Laura H.

Br J Pharmacol; 181(1): 87-106, 2024 01.

Artículo en Inglés | MEDLINE | ID: mdl-37553894

3.

Default Mode Network Modulation by Psychedelics: A Systematic Review.

Gattuso, James J; Perkins, Daniel; Ruffell, Simon; Lawrence, Andrew J; Hoyer, Daniel; Jacobson, Laura H; Timmermann, Christopher; Castle, David; Rossell, Susan L; Downey, Luke A; Pagni, Broc A; Galvão-Coelho, Nicole L; Nutt, David; Sarris, Jerome.

Int J Neuropsychopharmacol; 26(3): 155-188, 2023 03 22.

Artículo en Inglés | MEDLINE | ID: mdl-36272145

4.

Altered EEG power spectrum, but not sleep-wake architecture, in HCN1 knockout mice.

Bleakley, Lauren E; Keenan, Ryan J; Graven, Rachel D; Metha, Jeremy A; Ma, Sherie; Daykin, Heather; Cornthwaite-Duncan, Linda; Hoyer, Daniel; Reid, Christopher A; Jacobson, Laura H.

Behav Brain Res; 437: 114105, 2023 02 02.

Artículo en Inglés | MEDLINE | ID: mdl-36089097

5.

Orexin Signaling: A Complex, Multifaceted Process.

Dale, Natasha C; Hoyer, Daniel; Jacobson, Laura H; Pfleger, Kevin D G; Johnstone, Elizabeth K M.

Front Cell Neurosci; 16: 812359, 2022.

Artículo en Inglés | MEDLINE | ID: mdl-35496914

6.

Losing sleep with age.

Jacobson, Laura H; Hoyer, Daniel.

Science; 375(6583): 816-817, 2022 02 25.

Artículo en Inglés | MEDLINE | ID: mdl-35201892

7.

Differential sleep/wake response and sex differences following acute suvorexant, MK-1064 and zolpidem administration in the rTg4510 mouse model of tauopathy.

Keenan, Ryan J; Daykin, Heather; Chu, Jiahui; Cornthwaite-Duncan, Linda; Allocca, Giancarlo; Hoyer, Daniel; Jacobson, Laura H.

Br J Pharmacol; 179(13): 3403-3417, 2022 07.

Artículo en Inglés | MEDLINE | ID: mdl-35112344

8.

Hypocretins (orexins): The ultimate translational neuropeptides.

Jacobson, Laura H; Hoyer, Daniel; de Lecea, Luis.

J Intern Med; 291(5): 533-556, 2022 05.

Artículo en Inglés | MEDLINE | ID: mdl-35043499

9.

Discovery of Umibecestat (CNP520): A Potent, Selective, and Efficacious ß-Secretase (BACE1) Inhibitor for the Prevention of Alzheimer's Disease.

Machauer, Rainer; Lueoend, Rainer; Hurth, Konstanze; Veenstra, Siem J; Rueeger, Heinrich; Voegtle, Markus; Tintelnot-Blomley, Marina; Rondeau, Jean-Michel; Jacobson, Laura H; Laue, Grit; Beltz, Karen; Neumann, Ulf.

J Med Chem; 64(20): 15262-15279, 2021 10 28.

Artículo en Inglés | MEDLINE | ID: mdl-34648711

10.

Synthesis of the Potent, Selective, and Efficacious ß-Secretase (BACE1) Inhibitor NB-360.

Rueeger, Heinrich; Lueoend, Rainer; Machauer, Rainer; Veenstra, Siem J; Holzer, Philipp; Hurth, Konstanze; Voegtle, Markus; Frederiksen, Mathias; Rondeau, Jean-Michel; Tintelnot-Blomley, Marina; Jacobson, Laura H; Staufenbiel, Matthias; Laue, Grit; Neumann, Ulf.

J Med Chem; 64(8): 4677-4696, 2021 04 22.

Artículo en Inglés | MEDLINE | ID: mdl-33844524

11.

Manipulation of rapid eye movement sleep via orexin and GABAA receptor modulators differentially affects fear extinction in mice: effect of stable versus disrupted circadian rhythm.

Clark, Jacob W; Daykin, Heather; Metha, Jeremy A; Allocca, Giancarlo; Hoyer, Daniel; Drummond, Sean P A; Jacobson, Laura H.

Sleep; 44(9)2021 09 13.

Artículo en Inglés | MEDLINE | ID: mdl-33720375

12.

Reward motivation and cognitive flexibility in tau null-mutation mice.

Oberrauch, Sara; Metha, Jeremy A; Brian, Maddison L; Barnes, Samuel A; Featherby, Travis J; Lawrence, Andrew J; Hoyer, Daniel; Murawski, Carsten; Jacobson, Laura H.

Neurobiol Aging; 100: 106-117, 2021 04.

Artículo en Inglés | MEDLINE | ID: mdl-33524848

13.

Decreased Orexin Receptor 1 mRNA Expression in the Locus Coeruleus in Both Tau Transgenic rTg4510 and Tau Knockout Mice and Accompanying Ascending Arousal System Tau Invasion in rTg4510.

Keenan, Ryan J; Oberrauch, Sara; Bron, Romke; Nowell, Cameron J; Challis, Leesa M; Hoyer, Daniel; Jacobson, Laura H.

J Alzheimers Dis; 79(2): 693-708, 2021.

Artículo en Inglés | MEDLINE | ID: mdl-33361602

14.

Effects of orexin receptor antagonism on human sleep architecture: A systematic review.

Clark, Jacob W; Brian, Maddison L; Drummond, Sean P A; Hoyer, Daniel; Jacobson, Laura H.

Sleep Med Rev; 53: 101332, 2020 10.

Artículo en Inglés | MEDLINE | ID: mdl-32505969

15.

Circadian disruption impairs fear extinction and memory of conditioned safety in mice.

Clark, Jacob W; Hoyer, Daniel; Cain, Sean W; Phillips, Andrew; Drummond, Sean P A; Jacobson, Laura H.

Behav Brain Res; 393: 112788, 2020 09 01.

Artículo en Inglés | MEDLINE | ID: mdl-32598999

16.

Novel alterations in corneal neuroimmune phenotypes in mice with central nervous system tauopathy.

Jiao, Haihan; Downie, Laura E; Huang, Xin; Wu, Mengliang; Oberrauch, Sara; Keenan, Ryan J; Jacobson, Laura H; Chinnery, Holly R.

J Neuroinflammation; 17(1): 136, 2020 Apr 28.

Artículo en Inglés | MEDLINE | ID: mdl-32345316

17.

Hypnotics with novel modes of action.

Hoyer, Daniel; Allen, Andrew; Jacobson, Laura H.

Br J Clin Pharmacol; 86(2): 244-249, 2020 02.

Artículo en Inglés | MEDLINE | ID: mdl-31756268

18.

Sex differences in mouse models of fear inhibition: Fear extinction, safety learning, and fear-safety discrimination.

Clark, Jacob W; Drummond, Sean P A; Hoyer, Daniel; Jacobson, Laura H.

Br J Pharmacol; 176(21): 4149-4158, 2019 11.

Artículo en Inglés | MEDLINE | ID: mdl-30710446

19.

Separating Probability and Reversal Learning in a Novel Probabilistic Reversal Learning Task for Mice.

Metha, Jeremy A; Brian, Maddison L; Oberrauch, Sara; Barnes, Samuel A; Featherby, Travis J; Bossaerts, Peter; Murawski, Carsten; Hoyer, Daniel; Jacobson, Laura H.

Front Behav Neurosci; 13: 270, 2019.

Artículo en Inglés | MEDLINE | ID: mdl-31998088

20.

The social defeat/overcrowding murine psychosocial stress model results in a pharmacologically reversible body weight gain but not depression - related behaviours.

Keenan, Ryan J; Chan, Jacky; Donnelly, Paul S; Barnham, Kevin J; Jacobson, Laura H.

Neurobiol Stress; 9: 176-187, 2018 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-30450383

Portal Regional de la BVS Paraguay

Información y Conocimiento para la Salud

Configurar filtros

Su selección (0)

Formato de exportación:

Exportar: