RESUMEN
Multi-parametric Magnetic Resonance Imaging (mp-MRI) and prostate membrane specific antigen positron emission tomography (PSMA-PET) CT scan in prostate cancer has led to enhanced detection of local and metastatic recurrence post-radiotherapy. A 59-year-old man presented with biochemical relapse following low dose rate brachytherapy for ISUP 2 T1cN0M0 prostate cancer (PCa). Despite strong biochemical and radiological evidence of radio-recurrent PCa in his right seminal vesicle, serial transperineal biopsies revealed benign tissue. He proceeded to Robot Assisted Salvage Seminal Vesiculectomy (RSSV) as a diagnostic procedure without complication. Histo-pathology confirmed a 23 × 17 × 13mm focus of Gleason 4 + 4 adenocarcinoma in the SV with clear surgical margins.