[Variability of cardiac rhythm in patients with a symptomatic renal hypertension and effect of ramipril on its changes].

Variability of cardiac rhythm and influence of Ramipril on it have been studied in 31 patients with a secondary renal hypertension of 1 and 2 stages. Obtained data have shown, that treatment with Ramipril normalizes neurohumoral regulation at the expense of decrease of excessive sympathetic stimulation and decrease of peripheral parasympathetic insufficiency rate. All above mentioned changes were accompanied by reduction in frequency and grade of blood pressure increase and improvement in tolerance to physical activity.

[Methodical aspects of postgraduate education of family physicians in internship].

The article presents some methodical issues on postgraduate education of physicians studying at Zaporozhye Institute for advanced physicians training, chair of family medicin. The authors showed the priority of programmed learning and modern educational technologies in postgraduate education of physicians.

[Effect of perindopril on hemostasis and functional status of pancreas in patients with ischemic heart disease]. / Vplyv peryndoprylu na hemostaz ta funktsional'nyi stan pidshlunkovoï zalozy u khvorykh na ishemichnu khvorobu sertsia.

Systemic circulation compromise in patients with cardiac insufficiency results in disturbances of functional state of pancreas. The Willebrand's Factor takes a definite role in this pathological process. The usage of Peridopril 4 mg daily during the treatment decreases significantly Willebrand's Factor activity and normalizes function of the pancreas.

[The diagnosis of chronic cholecystitis and pancreatitis]. / Diagnostika khronicheskogo kholetsistita i pankreatita.

Results are submitted of ultrasonic monitoring of gallbladder, pancreas and duodenum during the I, II, III phases of digestion in 186 patients who ranged from 30 to 60 years old. The form was studied of the gallbladder as was its size and location together with the volume, thickness of walls, presence of deformities; echogenicity of pancreas, outline, state of the main duct. Interdigestive duodenal motility and intracavitary pressure were recorded. Relationship has been established of the gallbladder and pancreas contraction phases to the condition of the intracavitary pressure in the duodenum.

[Instrumental methods for studying the pancreaticobiliary system]. / Instrumental'ni metody doslidzhennia pankreatobiliarnoï systemy.

Ultrasonic monitoring was conducted in patients with chronic cholecystitis, pancreatitis (n = 186) to study contractile and functional activities of the gallbladder, pancreas, duodenum. The motor and evacuatory function of the gallbladder and pancreas was found out to be dependable upon the phase dyskinesias of duodenum. An increased pressure in duodenal cavity tends to impair the processes of intracavitary digestion and motor and evacuatory function of the gallbladder, pancreas, and to affect the phase outflow of bile and pancreatic juice.

[The renin-angiotensin-aldosterone system in chronic heart failure]. / O sostoianii renin-angiotenzin-al'dosteronovoi sistemy pri khronicheskoi serdechnoi nedostatochnosti.

Renin-angiotensin-aldosterone system (RAAS) in patients with rheumatic valve defects clearly tends to activation which in its turn aggravate chronic heart failure (CHF). Plasma renin activity in CHF depends on the cause of the latter, humoral changes in rheumatic heart disease being the most considerable. At the same time activated RAAS was characteristic of patients with rhythm disorders. All this evidence an important role of morphological changes and affected intracardiac haemodynamics in development of humoral vicious circle.

[The left ventricular echocardiogram of mitral stenosis patients]. / Ekhokardiogramma levogo zheludochka u bol'nykh mitral'nym stenozom.

The method of echocardiography was used to examine 71 patients with rheumatic stenosis of rheumatic etiology with different stages of cardiac insufficiency. Results of these investigations allowed to evaluate the hemodynamics, function of filling of the left ventricle, their relationship with velocity and time indices of the myocardium, with functional state of the mitral valve.

[Efficacy of corvaton in the long-term ambulatory treatment of heart failure in patients with rheumatic heart lesions]. / Effektivnost' korvatona v protsesse dlitel'nogo ambulatornogo lecheniia serdechnoi nedostatochnosti u bol'nykh revmaticheskimi porokami serdtsa.

Corvaton treatment of 23 patients with congestive heart failure caused by rheumatic valvular heart diseases, continued for 10 mos. An increase in the stroke and minute blood volume in the chest, leg and fingers, and a decrease in the peripheral vascular resistance and systolic pressure in the pulmonary artery were noted as a result of corvaton therapy. Corvaton efficacy was assessed by change in hemodynamics for 2 h after administration of the drug at a single dose of 4 mg. A response of hemodynamics to corvaton was preserved for 10 mos.